Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/ncpneuro0848 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Diagnosis of Parkinson's disease by eliciting trait-specific eye movements in multi-visual tasks.
J Transl Med
January 2025
School of Information and Communication Engineering, Dalian University of Technology, No. 2 Linggong Road, 116024, Dalian, China.
Background: Parkinson's Disease (PD) is a neurodegenerative disorder, and eye movement abnormalities are a significant symptom of its diagnosis. In this paper, we developed a multi-task driven by eye movement in a virtual reality (VR) environment to elicit PD-specific eye movement abnormalities. The abnormal features were subsequently modeled by using the proposed deep learning algorithm to achieve an auxiliary diagnosis of PD.
View Article and Find Full Text PDFDistinct detection and discrimination sensitivities in visual processing of real versus unreal optic flow.
Psychon Bull Rev
January 2025
NYU-ECNU Institute of Brain and Cognitive Science, New York University Shanghai, Shanghai, China.
We examined the intricate mechanisms underlying visual processing of complex motion stimuli by measuring the detection sensitivity to contraction and expansion patterns and the discrimination sensitivity to the location of the center of motion (CoM) in various real and unreal optic flow stimuli. We conducted two experiments (N = 20 each) and compared responses to both "real" optic flow stimuli containing information about self-movement in a three-dimensional scene and "unreal" optic flow stimuli lacking such information. We found that detection sensitivity to contraction surpassed that to expansion patterns for unreal optic flow stimuli, whereas this trend was reversed for real optic flow stimuli.
View Article and Find Full Text PDFNanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning.
Nat Biotechnol
January 2025
Institute for Intelligent Biotechnologies (iBIO), Helmholtz Center Munich, Neuherberg, Germany.
Efficient and accurate nanocarrier development for targeted drug delivery is hindered by a lack of methods to analyze its cell-level biodistribution across whole organisms. Here we present Single Cell Precision Nanocarrier Identification (SCP-Nano), an integrated experimental and deep learning pipeline to comprehensively quantify the targeting of nanocarriers throughout the whole mouse body at single-cell resolution. SCP-Nano reveals the tissue distribution patterns of lipid nanoparticles (LNPs) after different injection routes at doses as low as 0.
View Article and Find Full Text PDFReprogramming of updated neurostimulators in chronically implanted patients with Parkinson's disease: a double-blind randomized controlled trial.
Brain Stimul
January 2025
Edmond J. Safra Program in Parkinson's Disease and Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital, UHN, and Division of Neurology, University of Toronto, Toronto, Ontario, Canada; Krembil Brain Institute, Toronto, ON, Canada; CenteR for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada. Electronic address:
Multi-Scale Pyramid Squeeze Attention Similarity Optimization Classification Neural Network for ERP Detection.
Neural Netw
January 2025
Key Laboratory of Smart Manufacturing in Energy Chemical Process, Ministry of Education, East China University of Science and Technology, Shanghai 200237, China; Center of Intelligent Computing, School of Mathematics, East China University of Science and Technology, Shanghai 200237, China. Electronic address:
Event-related potentials (ERPs) can reveal brain activity elicited by external stimuli. Innovative methods to decode ERPs could enhance the accuracy of brain-computer interface (BCI) technology and promote the understanding of cognitive processes. This paper proposes a novel Multi-Scale Pyramid Squeeze Attention Similarity Optimization Classification Neural Network (MS-PSA-SOC) for ERP Detection.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!