AI Article Synopsis
- Spinal cord injuries often lead to long-lasting disabilities, but stem cell transplantation shows promise for recovery in animal studies.
- An alternative method involves activating the body's own neural stem cells located in the adult spinal cord for regeneration.
- The discussion includes potential benefits, risks, and mechanisms related to using stem cells for spinal cord healing.
Article Abstract
Spinal cord injury typically results in permanent disability. Many studies have indicated that transplantation of several different types of stem cells promotes functional recovery in animal models of spinal cord injury. A conceptually different approach to utilize stem cells for regenerative therapies may be recruitment of endogenous neural stem cells resident in the adult spinal cord. We discuss the possibilities, risks, and mechanisms for stem cells in spinal cord repair.
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| http://dx.doi.org/10.1016/j.stem.2008.06.011 | DOI Listing |
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