Spinal cord injuries will not disappear, but the incidence can be reduced. A reduction of up to 50% of spinal cord injury cases is, in the opinion of Menzies' seminar participants, practical and possible but will only occur if the subject is accepted as a major challenge in the surgical world. Great advances in spinal cord injury care were made by surgeons. Prevention is a programme already targeted in other surgical areas. As a multidisciplinary medical and surgical area, spinal cord injury prevention now needs the effective activity of groups of health professionals. Primary prevention must therefore be a target for surgical communities. Surgeons should be among the leaders in the field ensuring good overall management of prevention programmes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1445-2197.1991.tb00272.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Progress in spinal cord organoid research: advancing understanding of neural development, disease modelling, and regenerative medicine.
Biomater Transl
November 2024
Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education, Department of Orthopedics, Tongji Hospital affiliated to Tongji University, School of Life Science and Technology, Tongji University, Shanghai, China.
Stem cell-derived spinal cord organoids (SCOs) have revolutionised the study of spinal cord development and disease mechanisms, offering a three-dimensional model that recapitulates the complexity of native tissue. This review synthesises recent advancements in SCO technology, highlighting their role in modelling spinal cord morphogenesis and their application in neurodegenerative disease research. We discuss the methodological breakthroughs in inducing regional specification and cellular diversity within SCOs, which have enhanced their predictive ability for drug screening and their relevance in mimicking pathological conditions such as neurodegenerative diseases and neuromuscular disorders.
View Article and Find Full Text PDFCommunity Integration of Disability: A Bibliometric and Knowledge-Map Analysis.
J Multidiscip Healthc
January 2025
School of Nursing, Ningxia Medical University, Yinchuan, People's Republic of China.
Background: Community integration (CI) is the ultimate goal of rehabilitation for individuals with disabilities. It plays a significant role in restoring their social functioning and facilitating their reintegration into community and family life. However, no studies have utilized bibliometric methods to explore community integration.
View Article and Find Full Text PDFNon-saponin from maintains blood-brain barrier integrity by inhibiting NF-κB and p38 MAP kinase signaling pathways to prevent the progression of experimental autoimmune encephalomyelitis.
J Ginseng Res
January 2025
Department of Convergence Medical Science, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Background: The non-saponin (NS) fraction is an important active component of with multifunctional pharmacological activities including neuroprotective, immune regulatory, anti-inflammatory, and antioxidant effects. However, the effects of NSs on multiple sclerosis (MS), a chronic and autoimmune demyelinating disorder, have not yet been demonstrated.
Purpose: and Methods: The goal of the present study was to demonstrate the pharmacological actions of NSs on movement dysfunctions and the related mechanisms of action using an experimental autoimmune encephalomyelitis (EAE) mouse model of MS.
Establishing an Electrophysiological Recording Platform for Epidural Spinal Cord Stimulation in Neuropathic Pain Rats.
J Pain Res
January 2025
Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Purpose: Spinal cord stimulation (SCS) is pivotal in treating chronic intractable pain. To elucidate the mechanism of action among conventional and current novel types of SCSs, a stable and reliable electrophysiology model in the consensus animals to mimic human SCS treatment is essential. We have recently developed a new in vivo implantable pulsed-ultrahigh-frequency (pUHF) SCS platform for conducting behavioral and electrophysiological studies in rats.
View Article and Find Full Text PDFProgrammable scanning diffuse speckle contrast imaging of cerebral blood flow.
Neurophotonics
January 2025
University of Kentucky, Department of Biomedical Engineering, Lexington, Kentucky, United States.
Significance: Cerebral blood flow (CBF) imaging is crucial for diagnosing cerebrovascular diseases. However, existing large neuroimaging techniques with high cost, low sampling rate, and poor mobility make them unsuitable for continuous and longitudinal CBF monitoring at the bedside.
Aim: We aimed to develop a low-cost, portable, programmable scanning diffuse speckle contrast imaging (PS-DSCI) technology for fast, high-density, and depth-sensitive imaging of CBF in rodents.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!