AI Article Synopsis
- The paper outlines a method for using near-infrared diffuse reflectance spectroscopy to identify and quantify ranitidine in various pharmaceutical forms using a fiber optic probe.
- This method was developed for routine use in the pharmaceutical industry to replace traditional reference methods and has been approved by the National Medicine Regulatory Agency (Infarmed).
- The authors view this as an initial step towards a broader approach to the parametric release of pharmaceutical products.
Article Abstract
In this paper we describe the strategy used in the development and validation of a near-infrared diffuse reflectance spectroscopy method for identification and quantification of ranitidine in pharmaceutical products (granulates, cores and coated tablets) at-line, with a fiber optic probe. This method was developed in a pharmaceutical industry for routine application, to replace reference methods and was submitted and approved to the National Medicine Regulatory Agency (Infarmed). We consider that this is the first step of a broader parametric release approach to pharmaceutical products.
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| http://dx.doi.org/10.1016/j.talanta.2007.12.008 | DOI Listing |
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