We report a new phenomenon in cross-modal cuing of visual spatial attention-simultaneous auditory peripheral cues are "hyper-effective"-more effective than auditory peripheral (AP), visual central (VC), or visual peripheral (VP) cues that preceded the target with ample time for preparatory orienting. The time courses and mechanisms of visual spatial attention were measured in a four-location Gabor orientation identification task for targets embedded in systematically varying amounts of external noise [Lu, Z. -L., & Dosher, B. A. (1998). External noise distinguishes attention mechanisms. Vision Research, 38 (9), 1183-1198] and for cue-target asynchronies (CTOAs) between 0 and 240ms. Large CTOA pre-cuing improvements in contrast thresholds occurred in high external noise conditions for AP, VC, and VP cues. In low external noise conditions, pre-cuing advantages occurred for visual peripheral (VP) cues, but not for visual central cues (VC), replicating Lu and Dosher [Lu, Z. -L., & Dosher, B. A. (2000). Spatial attention: Different mechanisms for central and peripheral temporal precues? Journal of Experimental Psychology: Human Perception and Performance, 26 (5), 1534-1548]. Auditory peripheral pre-cues (AP) were similar to VP cues at large cue-target delays, but demonstrated a large cross-modal cuing advantage for simultaneous auditory peripheral cues (AP) in both high and low external noise. We conclude that endogenous attention (visual central pre-cuing) excludes external noise, while exogenous attention (both visual and auditory peripheral pre-cuing) enhances the stimulus but also excludes external noise if informative peripheral cues are used.
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http://dx.doi.org/10.1016/j.visres.2008.05.021 | DOI Listing |
Sensory neurons must be reproducibly specified to permit accurate neural representation of external signals but also able to change during evolution. We studied this paradox in the olfactory system by establishing a single-cell transcriptomic atlas of all developing antennal sensory lineages, including latent neural populations that normally undergo programmed cell death (PCD). This atlas reveals that transcriptional control is robust, but imperfect, in defining selective sensory receptor expression.
View Article and Find Full Text PDFJ Med Imaging (Bellingham)
January 2025
U.S. Food and Drug Administration, Office of Science and Engineering Labs, Division of Imaging, Diagnostics, and Software Reliability, Silver Spring, Maryland, United States.
Purpose: We evaluate the impact of charge summing correction on a cadmium telluride (CdTe)-based photon-counting detector in breast computed tomography (CT).
Approach: We employ a custom-built laboratory benchtop system using the X-THOR FX30 0.75-mm CdTe detector (Varex Imaging, Salt Lake City, Utah, United States) with a pixel pitch of 0.
Prog Neurobiol
January 2025
Department of Biomedicine, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland. Electronic address:
The brain faces the challenging task of preserving a consistent portrayal of the external world in the face of disruptive sensory inputs. What alterations occur in sensory representation amidst noise, and how does brain activity adapt to it? Although it has previously been shown that background white noise (WN) decreases responses to salient sounds, a mechanistic understanding of the brain processes responsible for such changes is lacking. We investigated the effect of background WN on neuronal spiking activity, membrane potential, and network oscillations in the mouse central auditory system.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Institute of Semiconductor Technology (IHT), Technische Universität Braunschweig, Hans-Sommer-Straße 66, 38106 Braunschweig, Germany.
A novel piezoresistive cantilever microprobe (PCM) with an integrated electrothermal or piezoelectric actuator has been designed to replace current commercial PCMs, which require external actuators to perform contact-resonance imaging (CRI) of workpieces and avoid unwanted "forest of peaks" observed at large travel speed in the millimeter-per-second range. Initially, a PCM with integrated resistors for electrothermal actuation (ETA) was designed, built, and tested. Here, the ETA can be performed with a piezoresistive Wheatstone bridge, which converts mechanical strain into electrical signals by boron diffusion in order to simplify the production process.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Department of Life Sciences, Ben Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Phenotypic variability in isogenic bacterial populations is a remarkable feature that helps them cope with external stresses, yet it is incompletely understood. This variability can stem from gene expression noise and/or the unequal partitioning of low-copy-number freely diffusing proteins during cell division. Some high-copy-number components are transiently associated with almost immobile large assemblies (hyperstructures) and may be unequally distributed, contributing to bacterial phenotypic variability.
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