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Development and Characterization of Oral Efavirenz-Loaded Nanostructured Lipid Carriers and Their Optimization with Box-Behnken Design Approach for the Neurological Disorder.
Assay Drug Dev Technol
January 2025
Department of Pharmaceutics, School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, New Delhi, India.
In vitro In vitro
View Article and Find Full Text PDFBehcet syndrome: A rare cause of recurrent genital ulceration.
Indian J Sex Transm Dis AIDS
December 2024
Department of Dermatology, Venereology and Leprosy, Government Medical College and S.S.G. Hospital, Vadodara, Gujarat, India.
Behcet syndrome (BS) is a chronic relapsing multisystem vasculitis with skin findings with an important contribution of genetics. Here, we present a case of a 16-year-old male with a complaint of recurrent genital, and oral ulceration with skin lesions and a history of recurrent thrombophlebitis at the sites of venepuncture. There were no systemic manifestations.
View Article and Find Full Text PDFUnveiling epilepsia partialis continua as an early indicator of HIV encephalitis.
Indian J Sex Transm Dis AIDS
December 2024
Department of Internal Medicine, AFMC, Pune, India.
A young male with no known addictions and comorbidities presenting with recurrent clonic-myoclonic movements, initially localized to the left corner of the mouth and left upper limb, evolving into epilepsia partialis continua, despite appropriate sequential antiepileptic medications, subsequently progressed to refractory status epilepticus. He was tested positive for HIV infection and his neuroimaging revealed nonenhancing lesions, a novel finding in HIV-related encephalitis. We managed him with intravenous immunoglobulin along with multiple antiepileptic medications and highly active antiretroviral therapy (ART), and he exhibited a rapid clinical recovery over 3 weeks.
View Article and Find Full Text PDFPregnancy-associated systemic lupus erythematosus in people living with HIV/AIDS.
Indian J Sex Transm Dis AIDS
October 2024
Department of Dermatology, Lady Hardinge Medical College, New Delhi, India.
Pregnancy with systemic lupus erythematosus (SLE) requires special attention in view of the enhanced risks to the fetus and the aggravation of SLE during pregnancy. Human immunodeficiency virus infection can further complicate the course of pregnancy as well as the outcome. We present a case of a 28-year-old primigravida who was diagnosed case of people living with HIV/AIDS and presented with SLE at 34 weeks of gestation.
View Article and Find Full Text PDFMultifaceted lichen planus: Vulvovaginal-gingival syndrome with coexisting cutaneous, nail, and hair manifestations in a singular clinical saga.
Indian J Sex Transm Dis AIDS
December 2024
Department of Dermatology, Government Medical College, Patiala, Punjab, India.
Lichen planus (LP) is a chronic inflammatory disorder primarily affecting the skin and mucous membranes, characterized by pruritic, violaceous papules often exhibiting a polygonal pattern. This dermatological disorder can affect various sites of the body, including the skin, nails, hair, and mucous membranes out of which the oral mucosa is the most commonly affected. We report a case of a 40-year-old female with a unique combination of cutaneous, nail, and mucosal LP manifestations coexisting with lichen planopilaris and vulvovaginal-gingival syndrome.
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