Coping is defined by Perlin and Shooler as "... that behavior that protects people from psychological pressure due to social situations and problems". This intention Lazarus and Folkman affirm: "... the coping allows people to use different abilities to manage the difficulties (stressors) that they experience in daily existence..." When the stressor is diabetes, the requirements and pressures due to the illness and its physiological and psychosocial consequences are continuous and become chronic. In numerous studies, the coping, suitable or not, has been linked to different medical consequences of the diabetes: changes in glycosylated hemoglobin levels, in the physiological functionality, in the specific symptomatology, in body weight and body mass index. In other research, as in the present contribution, the coping and specific socio-cognitive dimensions have been correlated with the psychosocial consequences of the diabetes, particularly with quality of life and psychological and social adaptation (PSA). This last concept refers, within the illness process, to the attainment of the characteristic behavioral and psychological objectives of recovery. The purpose of the present work is to individualize the coping styles and to note the correlations with socio-cognitive dimensions in diabetic patients, and to measure their incidence on the APS, answering to a series of questions, such as: "What are the modalities of a more functional coping? Are they correlated with the socio-cognitive dimensions? Together do they influence the APS processes?". To 123 diabetic patients (51 with diabetes type 1; 72 with diabetes type 2), with a middle age of 63.7 and 54.9, respectively, have been administered, in sequence, two questionnaires: an adaptation of the Bernese Coping Modes (BECOMO) of Heim et coll. and the Multidimensional Diabetes Questionnaire (MDQ) of Talbot et coll. The results, by using descriptive statistics and data analysis techniques, seem to point out that, in the two groups of diabetic patients, it is possible to identify different modalities of coping that favors both different levels of APS and categories of dissimilar APS.
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Curr Pharm Des
January 2025
Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy.
Background: In recent years, sodium-glucose co-transporter 2 inhibitors (SGLT2i) have emerged as a valuable treatment for type 2 diabetes (T2D) and heart failure. Despite these medications seeming to be safe in older people, the literature about SGLT2i and frailty is still limited. This study aims to evaluate whether SGLT2i use is associated with increased survival in older adults and if frailty can affect the findings.
View Article and Find Full Text PDFEndocr Metab Immune Disord Drug Targets
January 2025
Department of Laboratory Medicine, Taizhou First People's Hospital, Huangyan Hospital of Wenzhou Medical University, Taizhou, Zhejiang, China.
Aim: The aim of this study is to examine the role of the microrchidia (MORC) family, a group of chromatin remodeling proteins, as the therapeutic and prognostic markers for colorectal cancer (CRC).
Background: MORC protein family genes are a highly conserved nucleoprotein superfamily whose members share a common domain but have distinct biological functions. Previous studies have analyzed the roles of MORCs as epigenetic regulators and chromatin remodulators; however, the involvement of MORCs in the development and pathogenesis of CRC was less examined.
Curr Med Chem
January 2025
Cukurova University, Faculty of Medicine, Division of Endocrinology, Adana, Turkey.
Introduction: Diabetes mellitus is associated with an increased risk of atherosclerosis related to dyslipidemia. Although the terms hyperlipidemia and Diabetes Mellitus [DM] or diabetic dyslipidemia are interrelated to each other, these two conditions have some differences.
Aim: This study aimed to highlight possible mechanisms of hyperlipidemia and/or dyslipidemia in diabetic patients, which can be treated with available and newer hypolipidemic drugs.
Ann Ig
January 2025
Faculty of Medicine, University Vita-Salute San Raffaele, Milan, Italy.
Background: Glaucoma, diabetic retinopathy, and age-related macular degeneration impose substantial economic burdens on healthcare systems due to their high prevalence and chronic nature. Nevertheless, comprehensive Italian data is limited. This study aims to collect Italian evidence on the economic impact of these conditions to support more effective healthcare planning.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
January 2025
Division of Endocrinology, Diabetes, & Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Context: A national assessment of osteoporosis drug therapy (ODT) use can inform the extent of underdiagnosis and undertreatment of osteoporosis.
Objective: The aim was to describe trends in ODT use by age, sex, fragility fracture, and documented osteoporosis.
Methods: This was a retrospective analysis of patient-quarter observations for adults aged ≥50 years with commercial or Medicare Advantage health insurance in the OptumLabs Data Warehouse between 2011 and 2022.
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