AI Article Synopsis
- The study investigated the link between chronic hepatitis B virus (HBV) genotypes and clinical outcomes in 92 patients.
- Sixteen patients had genotype B, while 71 had genotype C, and the remaining cases were either mixed or not confirmed.
- The findings showed no significant differences in clinical or histological data between patients with the two genotypes, despite some differences in ALT levels and liver cirrhosis incidence.
Article Abstract
Objective: To explore the relationship between chronic hepatitis B virus genotypes and clinical pathology.
Methods: HBV genotype was determined in 92 cases with chronic hepatitis B patients and the relationship between HBV genotypes and clinical, serological and histological data of the patients was analyzed.
Results: Sixteen cases were infected with HBV genotype B (17.4%), 71 with genotype C (77.2%), 3 with HBV classified as genotype B+C (3.2%) and in 2 (2.2%) cases HBV genotype was not confirmed. ALT level and HBV DNA load log value were (82.6+/-82) U/L, (84.7+/-71.5) U/L and (5.8+/-1.4), (5.9+/-1.5) respectively in genotypes B and C patients, in 8 cases of genotype C group liver cirrhosis was diagnosed, but no statistical significance was seen.
Conclusion: No significant differences in clinical, serological or histological data were detected between genotypes B and C patients.
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