Two cases with periadrenal paraganglioma are herein reported. Patient 1: A 26-year-old woman who presented with headache and hyperhidrosis was noted to have hypertension. Abdominal ultrasonography, computed tomography, magnetic resonance imaging, and I-tagged metaiodobenzylguanidine nuclear scintigraphy revealed a mass measuring 30 x 30 mm in size between the upper pole of the left kidney and the aorta. The value of urinary noradrenaline and normetanephrine were high. Patient 2: A 38-year-old woman who presented with headache and hyperhidrosis was noted to have hypertension. A preoperative imaging study revealed a mass measuring 20 x 20 mm in size between the upper pole of the left kidney and the aorta. The value of blood noradrenaline and urinary normetanephrine were high. In both cases, the paragangliomas were successfully removed laparoscopically without either any intraoperative or postoperative complications. Patient 1 is alive and doing well with no recurrence for 9 years, whereas patient 2 has been doing well for 3 years.
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