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Retrospective evaluation of the influence of phenoxybenzamine pretreatment on intraoperative cardiovascular variables in dogs with pheochromocytoma.
Can Vet J
December 2024
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA (Willette); Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA (Bini, Selmic); Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA (Traverson); Capital City Specialty & Emergency Animal Hospital, Ottawa, Ontario (Liptak); College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA (Hollenbeck); Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA (Maxwell, de Mello Souza); College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA (Wustefeld-Janssens).
Objective: To compare cardiovascular outcomes in dogs undergoing adrenalectomy for pheochromocytoma with and without phenoxybenzamine pretreatment.
Animals: A total of 65 medical records from dogs at 5 veterinary hospitals.
Procedure: Records from January 2004 to December 2021 were evaluated for systolic, mean, and diastolic arterial pressures; numbers of hypertensive and hypotensive episodes; highest and lowest systolic arterial pressure differences; dose and duration of phenoxybenzamine; and presence of intraoperative arrhythmias.
Identification and Analysis of Biomarkers Associated with Lipophagy and Therapeutic Agents for COVID-19.
Viruses
June 2024
Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Background: Lipids, as a fundamental cell component, play an regulating role in controlling the different cellular biological processes involved in viral infections. A notable feature of coronavirus disease 2019 (COVID-19) is impaired lipid metabolism. The function of lipophagy-related genes in COVID-19 is unknown.
View Article and Find Full Text PDFA comprehensive history of injection therapy for erectile dysfunction, 1982-2023.
Sex Med Rev
June 2024
San Diego Sexual Medicine, San Diego CA 92120, United States.
Introduction: Although oral phosphodiesterase 5 inhibitors represent a first choice and long-term option for about half of all patients with erectile dysfunction (ED), self-injection therapy with vasoactive drugs remains a viable alternative for all those who are not reacting or cannot tolerate oral drug therapy. This current injection therapy has an interesting history beginning in 1982.
Objectives: To provide a comprehensive history of self-injection therapy from the very beginnings in 1982 by contemporary witnesses and some members of the International Society for Sexual Medicine's History Committee, a complete history of injection therapy is prepared from eyewitness accounts and review of the published literature on the subject, as well as an update of the current status of self-injection therapy.
Cannabinoid hyperemesis and pheochromocytoma hypertensive urgency: a case report.
J Med Case Rep
March 2024
Department of Anesthesiology, Stanford University, 300 Pasteur Dr., Stanford, CA, 94305, USA.
Background: This report presents a case of cannabinoid-induced hyperemesis syndrome causing repeated violent retching in a patient with a large (8 cm) adrenal pheochromocytoma resulting in hypertensive urgency.
Case Presentation: A 69-year-old white male patient with a previously diagnosed pheochromocytoma presented to the emergency department with nausea and vomiting and was found to have hypertensive urgency. Computed tomography scan did not show any acute abdominal pathology and history was inconsistent with a gastrointestinal etiology.
Surgery for phaeochromocytomas and paragangliomas: Current practice in the United Kingdom.
Ann R Coll Surg Engl
September 2024
Introduction: There is wide variability in the perioperative management of phaeochromocytoma and paraganglioma (PPGL) in different centres. This study aimed to summarise the management of PPGLs as reported in the United Kingdom Registry for Endocrine and Thyroid Surgery (UKRETS) database and to determine current perioperative management of PPGLs by surveying UK clinicians.
Methods: Data recorded on UKRETS from 2005 to 2021 were subjected to descriptive analyses.
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