Vaccines against rotaviruses infections are the first vaccines used against gastro-enterity among young children. There are two actual used oral vaccines: Rotarix (GSK) and RotaTeq (MSD/Sanofi Pasteur). Both vaccines are live with atenuated strains of viruses. Vaccination should be performed between 6 and 24 weeks of life, most often between 6 and 6 weeks. Two doses of Rotarix, three doses of RotaTeq with 4 weeks distances of time between vactination are used as immunization. No booster doses are recommended. Vaccines used actually are succesful and safety, especially according intussusception after vaccination.
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Transplant-Free Approach in Relapsed Hodgkin Lymphoma in Children, Adolescents, and Young Adults: A Nonrandomized Clinical Trial.
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January 2025
Children's Wisconsin, Milwaukee.
Importance: Retrieval strategies for children, adolescents, and young adults with relapsed classic Hodgkin lymphoma (cHL) aim to maintain efficacy while minimizing long-term toxic effects. Children, adolescents, and young adults with low-risk, relapsed cHL may benefit from replacing high-dose chemotherapy and autologous stem cell transplant with less intensive involved-site radiotherapy (ISRT).
Objective: To evaluate a risk-stratified, response-adapted, transplant-free approach for treatment of children, adolescents, and young adults with low-risk relapsed cHL with nivolumab plus brentuximab vedotin (BV) followed by BV plus bendamustine for patients with suboptimal response and ISRT (30.
High incidence of tuberculosis in young children living with HIV in the Western Cape, South Africa.
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January 2025
Centre for Infectious Disease Epidemiology and Research, School of Public Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Background: Data on tuberculosis (TB) incidence and risk factors among children living with HIV (CLHIV) in the universal ART era are limited.
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JAMA Oncol
January 2025
Department of Paediatric Haematology, Oncology and Immunodeficiency, University Hospital Justus-Liebig University Giessen, Giessen, Germany.
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Invest Ophthalmol Vis Sci
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State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
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Trends and epidemiology of children treated in specialized burn centers in the Netherlands between 2009 and 2022.
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Alliance of Dutch Burn Care, Burn Center, Red Cross Hospital, PO Box 1074, 1940 EB, Beverwijk, the Netherlands.
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