The role of the nucleus pulposus in neutral zone human lumbar intervertebral disc mechanics.

J Biomech

Department of Materials Science and Engineering, Drexel University, 3141 Chestnut Street, Philadelphia, PA 19104, USA.

Published: July 2008

AI Article Synopsis

  • The study analyzed how removing the nucleus pulposus (denucleation) affects the mechanical properties of human lumbar intervertebral discs through a small incision.
  • Two groups of cadaver spinal units underwent tests in various movements after partial denucleation, measuring factors like range of motion and stiffness.
  • Results indicated that the nucleus pulposus plays a more significant role in the disc's mechanical behavior during smaller movements (neutral zone) compared to larger applied stress.

Article Abstract

To study the effect of denucleation on the mechanical behavior of the human lumbar intervertebral disc through a 2mm incision, two groups of six human cadaver lumbar spinal units were tested in axial compression, axial rotation, lateral bending and flexion/extension after incremental steps of "partial" denucleation. Neutral zone, range of motion, stiffness, intradiscal pressure and energy dissipation were measured; the results showed that the contribution of the nucleus pulposus to the mechanical behavior of the intervertebral disc was more dominant through the neutral zone than at the farther limits of applied loads and moments.

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http://dx.doi.org/10.1016/j.jbiomech.2008.04.037DOI Listing

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