Sub-Saharan Africa is a common destination for occupational travellers from South Africa. Adequate preventive measures require timeous medical consultation before travel. A secondary analysis of datasets of over 8000 occupational travellers who visited travel clinics in South Africa indicated that 82% were travelling to African countries and over 50% consulted less than a week before travel. For the 70% who consult less than 10 days before departure, yellow fever certificates issued at consultation would not be valid for entry to endemic countries, although they may be protected from contracting yellow fever. The 'last minute' travel medicine consultation appears to be more common in South Africa than in Europe and North America. This may preclude South African health professionals from providing occupational travellers adequate disease prevention, particularly against vaccine-preventable infectious diseases.
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http://dx.doi.org/10.1016/j.tmaid.2008.01.007 | DOI Listing |
Pharmazie
December 2024
Centre of Excellence for Pharmaceutical Sciences (Pharmacen™), North-West University, Potchefstroom, Republic of South Africa.
The COVID-19 pandemic caused global pandemonium, and due to an unprecedented global response, the popularity and use of (veterinary) ivermectin, amongst many other conceivable 'treatments', experienced a meteoric rise. Ivermectin is a macrocyclic lactone compound belonging to the avermectin drug class and is a registered medicine in many countries, although the most common use is as veterinary medicine. In this study, a fast HPLC method was developed and validated for the quantification of ivermectin in veterinary products that were used off-label by a substantial number of people during COVID-19.
View Article and Find Full Text PDFPediatr Res
January 2025
Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.
Background: This study aimed to investigate associations between sociodemographic factors and dietary intake among a diverse population of early adolescents ages 10-13 years in the United States.
Methods: We examined data from the Adolescent Brain Cognitive Development (ABCD) Study in Year 2 (2018-2020, ages 10-13 years, N = 10,280). Multivariable linear regression models were conducted to estimate the adjusted associations between sociodemographic factors (age, sex, race and ethnicity, household income, parental education) and dietary intake of various food groups, measured by the Block Kids Food Screener.
NPJ Vaccines
January 2025
Jiangzhong Cancer Research Center, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.
Tumor-derived exosomes (TDEs) mediate oncogenic communication, which modifies target cells to reinforce a tumor-promoting microenvironment. TDEs support cancer progression by suppressing anti-tumor immune responses, promoting metastasis, and conferring drug resistance. Thus, targeting TDEs could improve the efficacy of anti-cancer treatments and control metastasis.
View Article and Find Full Text PDFPediatr Blood Cancer
January 2025
Department of Pediatric Surgery, Pediatric Oncology Institute - GRAACC - Federal University of São Paulo, São Paulo, Brazil.
Background: Surgery remains the cornerstone of treatment for rhabdomyosarcoma (RMS) in children. However, there is considerable variation in surgical management practices worldwide, highlighting the need for standardized Clinical Practice Guidelines (CPG).
Methods: The CPG development involved assembling a multidisciplinary group, prioritizing 10 key topic areas, conducting evidence searches, and synthesizing findings.
BMJ Glob Health
January 2025
University of Bristol Musculoskeletal Research Unit, Bristol, Bristol, UK.
Introduction: Population ageing in Africa is increasing healthcare demands. Hip fractures require multidisciplinary care and are considered an indicator condition for age-related health services. We aimed to estimate current hip fracture incidence in Zimbabwe, compare rates against other regional estimates and estimate future fracture numbers.
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