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Comparing magnetic resonance enterography and endoscopy findings to the motility of magnetic resonance imaging in pediatric Crohn's disease.
Pediatr Radiol
January 2025
Pediatric Gastroenterology, Medical College of Wisconsin, B610 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
Background: Quantitative magnetic resonance imaging (MRI) can evaluate bowel motility in children with Crohn's disease. As inflammation increases, motility decreases.
Objective: Our aim was to show that quantitative MRI correlates with magnetic resonance enterography (MRE).
Efficacy of piracetam in children with breath-holding spells: a systematic review and meta-analysis.
Eur J Pediatr
December 2024
Pediatric Neurology Division, Department of Pediatrics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, 249203, India.
A number of randomized-controlled trials (RCTs) have been conducted comparing the efficacy of piracetam with placebo and other medications in children with breath-holding spells (BHS). However, no systematic review has yet collated all this evidence. All RCTs comparing the efficacy and/or safety of piracetam with placebo or other medications in children with BHS were included.
View Article and Find Full Text PDFA case report of verapamil toxicity leading to haemodynamic compromise in obstructive hypertrophic cardiomyopathy.
Eur Heart J Case Rep
December 2024
Department of Medicine, Division of Cardiology, University of California, Irvine, 333 City Blvd W, Orange, CA 92868, USA.
Background: Hypertrophic cardiomyopathy (HCM) is an inherited condition characterized by left ventricular (LV) hypertrophy unexplained by increased afterload, often with concomitant outflow tract obstruction. Verapamil is commonly used to treat symptomatic patients. However, its potential for adverse effects should be recognized.
View Article and Find Full Text PDFQuantitative mapping of cerebrovascular reactivity amplitude and delay with breath-hold BOLD fMRI when end-tidal CO quality is low.
bioRxiv
November 2024
Department of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Cerebrovascular reactivity (CVR), the ability of cerebral blood vessels to dilate or constrict in order to regulate blood flow, is a clinically useful measure of cerebrovascular health. CVR is often measured using a breath-hold task to modulate blood CO levels during an fMRI scan. Measuring end-tidal CO (PCO) with a nasal cannula during the task allows CVR amplitude to be calculated in standard units (vascular response per unit change in CO, or %BOLD/mmHg) and CVR delay to be calculated in seconds.
View Article and Find Full Text PDFThe blood flow and vascular responses in dynamically exercising skeletal muscles evoked by combination of cold stimulation and voluntary apnea in humans.
Eur J Appl Physiol
November 2024
Institute of Health and Sport Sciences, University of Tsukuba, Tsukuba City, Ibaraki, 305-8574, Japan.
Purpose: We evaluated (1) the combined effects of cold stimulation and voluntary breath holding (apnea) on heart rate, blood pressure, blood flow and vascular responses in dynamically exercising muscles in humans, and (2) if some interactions exist between cold stimulation and apnea on the cardiovascular responses.
Methods: Nine males and 1 female performed three trials entailing a dynamic two-legged knee extension exercise at a constant workload that elicited heart rates around 100 beats min. During the trials the participants performed either: (1) immersed their right hand into ice water maintained at 4 °C (cold pressor test; CPT); (2) performed maximal-duration apnea; and (3) performed a combination of CPT and apnea.
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