Unusually resistant post-traumatic uveitis with high serum ACE--an occult ocular sarcoidosis?

Purpose: The initiation of acute anterior uveitis following non-penetrating trauma comprises a defined clinical entity although its pathophysiology is not yet completely understood.

Design And Methods: Case presentation.

Results: We present two cases of young boys in whom a first episode of resistant anterior uveitis developed following relatively minor non penetrating ocular injury. Further investigation revealed high levels of serum ACE in both cases.

Conclusion: To the best of our knowledge there are no previous published reports implicating minor ocular trauma in precipitating a first episode of uveitis associated with high serum ACE. A better understanding of the pathophysiology may provide insight into alternative treatments.