Porphyromonas species are frequently isolated from the oral cavity and are associated with periodontal disease in both animals and humans. Black, pigmented Porphyromonas spp. isolated from the gingival margins of selected wild and captive Australian marsupials with varying degrees of periodontal disease (brushtail possums, koalas and macropods) were compared phylogenetically to Porphyromonas strains from non-marsupials (bear, wolf, coyote, cats and dogs) and Porphyromonas gingivalis strains from humans using 16S rRNA gene sequence analysis. The results of the phylogenetic analysis identified three distinct groups of strains. A monophyletic P. gingivalis group (Group 1) contained only strains isolated from humans and a Porphyromonas gulae group (Group 2) was divided into three distinct subclades, each containing both marsupial and non-marsupial strains. Group 3, which contained only marsupial strains, including all six strains isolated from captive koalas, was genetically distinct from P. gulae and may constitute a new Porphyromonas species.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1462-2920.2008.01668.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Effect of Oral Care Product Ingredients on Oral Pathogenic Bacteria Transcriptomics Through RNA-Seq.
Microorganisms
December 2024
Oral Care Product Development, The Procter & Gamble Company, Cincinnati, OH 45202, USA.
Various ingredients are utilized to inhibit the growth of harmful bacteria associated with cavities, gum disease, and bad breath. However, the precise mechanisms by which these ingredients affect the oral microbiome have not been fully understood at the molecular level. To elucidate the molecular mechanisms, a high-throughput bacterial transcriptomics study was conducted, and the gene expression profiles of six common oral bacteria, including two Gram-positive bacteria (, ) and four Gram-negative bacteria (, , , and ), were analyzed.
View Article and Find Full Text PDFBiosynthesis and Characterization of Silver Nanoparticles and Simvastatin Association in Titanium Biofilms.
Pharmaceuticals (Basel)
November 2024
Laboratório de Farmacologia de Antimicrobianos e Microbiologia, Faculdade de Ciências Farmacêuticas, Universidade Estadual de Campinas (UNICAMP), Campinas 13083-970, Brazil.
Introduction: Simvastatin is an antilipidemic drug that has already demonstrated antibacterial activities on oral and non-oral microorganisms. Silver nanoparticles also exhibit antimicrobial properties, particularly for coating implant surfaces. In this study, we evaluated the effects of combining simvastatin with silver nanoparticles on the formation and viability of biofilms consolidated on titanium discs.
View Article and Find Full Text PDFMicrobial community analysis of supragingival plaque in patients with fixed prostheses.
J Prosthet Dent
January 2025
Associate Professor, Department of Stomatology, The Fifth Affiliated Hospital of Sun Yat-sen University, Xiangzhou, Zhuhai City, Guangdong, PR China. Electronic address:
Statement Of Problem: Harmony between prostheses and periodontal tissues is essential. The presence of a fixed prosthesis has been reported to increase the risk of periodontal lesion onset in abutment teeth and to affect longevity. However, studies comparing the supragingival plaque biofilm on fixed prostheses and natural teeth are lacking.
View Article and Find Full Text PDFDynamin-Related Protein 1 Orchestrates Inflammatory Responses in Periodontal Macrophages via Interaction With Hexokinase 1.
J Clin Periodontol
January 2025
Department of Oral Implantology, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, China.
Aim: To explore the potential roles of mitochondrial dysfunction in the initiation of inflammation in periodontal macrophages and to determine the mechanism underlying the involvement of dynamin-related protein 1 (Drp1) in macrophage inflammatory responses through its interaction with hexokinase 1 (HK1).
Materials And Methods: Gingival tissues were collected from patients diagnosed with periodontitis or from healthy volunteers. Drp1 tetramer formation and phosphorylation were analysed using western blot.
Inhibitory effects of Colocasia antiquorum var. esculenta varnish on inflammation and alveolar bone loss in a rat ligature-induced periodontitis model.
Dent Mater J
December 2024
Institute of Biomaterials and Implant, College of Dentistry, Wonkwang University.
We aimed to evaluate whether Colocasia antiquorum var. esculenta (CA) mixed with experimental varnish inhibits inflammation and alveolar bone loss in a rat ligature-induced periodontitis model. The minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) were tested and cell viability of CA were also evaluated.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!