Objective: To measure the prevalence of the Brugada type 1 ECG pattern in the general population in the Philippines. STUDY SETTING AND DESIGN: Sudden unexplained death syndrome is rare in the West but is common among Southeast Asians. Ventricular fibrillation is the terminal event. The Brugada type 1 electrocardiographic (ECG) pattern with J point and coved ST elevation in right precordial leads, is a marker for sudden unexplained death syndrome. Its prevalence in the general population is unknown. A cross-sectional nationwide survey was performed in the Philippines in 2003 using a stratified multistage sampling design covering all the regions and provinces in the country. ECGs were performed in all adults surveyed. The prevalences of the Brugada type 1 ECG pattern (coved type) and any type Brugada ECG pattern were determined.
Results: The Brugada type 1 (coved) ECG pattern in the general population in the Philippines was found in 0.2% (95% Confidence Interval [CI] 0.03%-0.36%) of the population. Among males the prevalence was 0.3% (+/-0.1). The prevalence of any type Brugada ECG was 2% (95% CI 1.5%-2.6%).
Conclusion: The Brugada ECG pattern is common among Filipinos. There is a need to determine the risk of sudden death among individuals with this marker in the general population.
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http://dx.doi.org/10.1016/j.jclinepi.2007.11.009 | DOI Listing |
Patterns (N Y)
December 2024
Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
To achieve adequate trust in patient-critical medical tasks, artificial intelligence must be able to recognize instances where they cannot operate confidently. Ensemble methods are deployed to estimate uncertainty, but models in an ensemble often share the same vulnerabilities to adversarial attacks. We propose an ensemble approach based on feature decorrelation and Fourier partitioning for teaching networks diverse features, reducing the chance of perturbation-based fooling.
View Article and Find Full Text PDFJ Physiol
January 2025
Department of Biological Sciences, Southern Methodist University, Dallas, TX, USA.
Sudden unexpected death in epilepsy (SUDEP) is a devastating complication of epilepsy with possible sex-specific risk factors, although the exact relationship between sex and SUDEP remains unclear. To investigate this, we studied Kcna1 knockout (Kcna1) mice, which lack voltage-gated Kv1.1 channel subunits and are widely used as a SUDEP model that mirrors key features in humans.
View Article and Find Full Text PDFJ Interv Card Electrophysiol
January 2025
Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, No.180, Feng-Lin Road, Shanghai, 200032, P.R. China.
Background: Ventricular arrhythmia (VA) originating from the left ventricular summit (LVS) poses particular challenges, with higher rates of ablation failure.
Objective: To further evaluate the anatomical ablation approach from the subaortic region for LVS VAs and their electrophysiological characteristics.
Method: The study enrolled 27 consecutive patients with sympatomatic VAs originating from LVS and who received an anatomical ablation approach from R-L ILT in our center.
Sensors (Basel)
December 2024
REMIT (Research on Economics, Management and Information Technologies), IJP (Instituto Jurídico Portucalense), Universidade Portucalense, Rua Dr. António Bernardino de Almeida, 541-619, 4200-072 Porto, Portugal.
Some previous studies have focused on using physiological signals to detect stress in individuals with ASD through wearable devices, yet few have focused on how to design such solutions. Wearable technology may be a valuable tool to aid parents and caregivers in monitoring the emotional states of individuals with ASD who are at high risk of experiencing very stressful situations. However, effective wearable devices for individuals with ASD may need to differ from solutions for those without ASD.
View Article and Find Full Text PDFInt J Cardiol
January 2025
Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Padova, Italy. Electronic address:
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