Carcinosarcoma of the orbit: report of two cases and review of the literature.

Objective: To report the clinicopathologic features of 2 patients with carcinosarcoma of the orbit.

Design: Case reports.

Participants: Two patients with orbital carcinosarcoma were identified.

Methods: Retrospective chart review with clinicopathologic correlation and literature review.

Main Outcome Measures: Clinical examination, imaging studies, and histopathologic findings.

Results: Two patients, a 56-year-old woman and a 91-year-old woman, with orbital carcinosarcoma were identified. Both tumors contained sarcomatous and carcinomatous components and invaded periorbital structures.

Conclusions: Carcinosarcoma may arise in the orbit or extend into the orbit from the paranasal sinuses. This malignant neoplasm should be aggressively treated with a combination of surgical resection, chemotherapy, and radiation therapy.