Objective: Most studies that have investigated the symptom dimensions of schizophrenia utilizing the Scale for the Assessment of Positive Symptoms (SAPS) and the Scale for the Assessment of Negative Symptoms (SANS), both global rating scales, favored a 3-factor model. Only a few studies have examined the factor structure at the item level and they suggest a wider dimensional structure. The factor structure of schizophrenic symptoms has not been previously studied in Turkey, nor has the construct validity of these scales. The present study sought to determine the factor structure of the independent items and the construct validity of the scales.
Method: The study included 180 schizophrenia patients (diagnoses based on DSM-IV criteria). The standard statistical methods of principal component analysis (PCA) and varimax rotation were used to extract factors.
Results: PCA of the global items yielded a 3-factor solution, representing positive, negative, and disorganization dimensions. Item-level factor analysis revealed 12 factors: Psychomotor poverty, positive formal thought disorder, auditory/visual hallucinations, social and occupational dysfunction, bizarre delusions, attention/stereotypy, paranoid features, somatic hallucinations/delusions, appearance, grandiose/religious delusions, inappropriate affect, and delusions of jealousy.
Conclusion: Consistent with previous studies, neither the global nor the item-level factor structures supported the simple positive-negative dichotomy or the composition of the sub-scales; therefore, future studies should make use of the single items, especially when positive symptoms are being studied.
Download full-text PDF |
Source |
---|
Ecotoxicol Environ Saf
January 2025
State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China. Electronic address:
Honeybees, essential pollinators for maintaining biodiversity, are experiencing a sharp population decline, which has become a pressing environmental concern. Among the factors implicated in this decline, neonicotinoid pesticides, particularly those belonging to the fourth generation, have been the focus of extensive scrutiny due to their potential risks to honeybees. This study investigates the molecular basis of these risks by examining the binding interactions between Apis mellifera L.
View Article and Find Full Text PDFJ Neurosurg
January 2025
4Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, Tennessee; and.
Objective: This study aimed to investigate the extent of gender disparities in financial interactions between neurosurgeons and the medical device industry, examining the differences in the number, amount, and types of payments made to male and female neurosurgeons.
Methods: Utilizing data from the Centers for Medicare & Medicaid Services Open Payments database covering 2016-2022, the authors conducted a comprehensive analysis of industry payments to neurosurgeons. This methodology included univariate and multivariate analyses to examine the disparities in payments, with a focus on identifying significant differences in compensation across genders.
Adv Sci (Weinh)
January 2025
State Key Laboratory of Reproductive Medicine and Offspring Health, Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Perfluorohexane sulfonic acid (PFHxS) is extensively used in waterproof coatings and fire-fighting foams, and several studies have found it to be a potential health hazard, but there is still unknown about its effects on spermatogenesis. Our results showed that PFHxS-treated mice have significant reproductive toxicity, including a decrease in sperm count and motility, and the levels of sex hormones (P < 0.05).
View Article and Find Full Text PDFPLoS Comput Biol
January 2025
Department of Biomedical Informatics, University of Colorado Anschutz School of Medicine, Aurora, Colorado, United States of America.
While single-cell experiments provide deep cellular resolution within a single sample, some single-cell experiments are inherently more challenging than bulk experiments due to dissociation difficulties, cost, or limited tissue availability. This creates a situation where we have deep cellular profiles of one sample or condition, and bulk profiles across multiple samples and conditions. To bridge this gap, we propose BuDDI (BUlk Deconvolution with Domain Invariance).
View Article and Find Full Text PDFPLoS One
January 2025
Institute for Human Development, Aga Khan University, Nairobi, Kenya.
Introduction: Children growing up in arid and semi-arid regions of Sub-Saharan Africa (SSA) face heightened risks, often resulting in poor developmental outcomes. In Kenya, the arid and semi-arid lands (ASAL) exhibit the lowest health and developmental indicators among children. Despite these risks, some children grow up successfully and overcome the challenges.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!