Synthesis of an ent-halimanolide from ent-halimic acid.

Molecules

Departamento de Química Orgánica, Universidad de Salamanca, Plaza de los Caídos 1-5, 37008 Salamanca, Spain.

Published: May 2008

An efficient synthesis of ent-halimanolide 2 (15,16-epoxy-12-oxo-ent-halima- 5(10),13(16),14-trien-18,2beta-olide), from ent-halimic acid has been achieved, corroborating the structure of the natural compound and establishing its absolute configuration.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245183PMC
http://dx.doi.org/10.3390/molecules13051120DOI Listing

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Synthesis of an ent-halimanolide from ent-halimic acid.

Molecules

May 2008

Departamento de Química Orgánica, Universidad de Salamanca, Plaza de los Caídos 1-5, 37008 Salamanca, Spain.

An efficient synthesis of ent-halimanolide 2 (15,16-epoxy-12-oxo-ent-halima- 5(10),13(16),14-trien-18,2beta-olide), from ent-halimic acid has been achieved, corroborating the structure of the natural compound and establishing its absolute configuration.

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