Minor iridoids from the roots of Valeriana wallichii.

J Nat Prod

Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, People's Republic of China.

Published: July 2008

Four new iridoids, valeriotetrates B and C (1 and 2), 8-methylvalepotriate (3), and 1,5-dihydroxy-3,8-epoxyvalechlorine A (4), together with three known iridoids, were isolated from the roots of Valeriana wallichii. The structures of the new compounds were elucidated by analysis of 1D and 2D NMR and HRESIMS data. Compound 4 is an unusual iridoid bearing a C-10 chloro group and an oxo bridge connecting C-3 and C-8, resulting in a rigid skeleton.

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http://dx.doi.org/10.1021/np070598pDOI Listing

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