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This study investigates whether lower self-regulation (SR) facets are risk factors for internalizing symptoms (vulnerability models), consequences of these symptoms (scar models), or develop along the same continuum and thus share common causes (spectrum models) during middle childhood. To analyze these models simultaneously, a random intercept cross-lagged panel model was estimated using Mplus. Data were assessed at three measurement time points in a community-based sample of = 1657 (52.
View Article and Find Full Text PDFThe introduction of the SARS-CoV-2 BA.4 lineage into Pakistan.
Arch Virol
January 2025
Department of Virology, National Institute of Health (NIH), 45500, Park Rd, Chak Shahzad, Islamabad, Pakistan.
Pakistan has experienced a total of six COVID-19 waves throughout the pandemic, each driven by distinct SARS-CoV-2 lineages. This study explores the introduction of Omicron lineage BA.4 into Pakistan, which contributed to the sixth wave between June and September 2022.
View Article and Find Full Text PDFArticle Synopsis
- ADHD is a treatable condition, but children from racial-ethnic minority backgrounds often face barriers to timely and consistent treatment.
- Understanding the effects of systemic racism on healthcare can help improve ADHD care for these families.
- The experiences of families of color, along with guidance from healthcare professionals, can inform better clinical practices and foster equitable treatment for ADHD.
Simulating success: Applying EPA assessments to simulation in surgical education.
Surgery
January 2025
Department of Surgery, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL. Electronic address:
Entrustable professional activities are a competency-based evaluation framework which was deployed by the American Board of Surgery in 2023 to evaluate general surgical residents and provide a path to independent practice. Entrustable professional activity microassessments are based on 18 conditions which are core to being a practicing general surgeon, and most include multiple phases of care, such as preoperative care, intraoperative care, and postoperative care. These evaluations are an amalgam of all the clinical competencies, including medical knowledge and patient care skills.
View Article and Find Full Text PDFImpaired coagulation parameters in early RA are restored by effective antirheumatic therapy: a prospective pilot study.
RMD Open
December 2024
Rheumatology, Amsterdam UMC Locatie VUmc, Amsterdam, The Netherlands
Objectives: To assess the effect of treatment on haemostatic parameters in patients with early rheumatoid arthritis (RA).
Methods: Patients with newly diagnosed RA started methotrexate and were randomised to additional conventional treatment, certolizumab pegol, abatacept or tocilizumab. Several biomarkers for haemostasis were analysed including parameters of the two global haemostatic assays-overall haemostatic potential (OHP) and endogenous thrombin potential (ETP), as well as single haemostatic factors-fibrinogen, prothrombin fragment 1+2 (F1+2), D-dimer, thrombin activatable fibrinolysis inhibitor (TAFI) and clot lysis time (CLT) in 24 patients at baseline, 12 and 24 weeks after the start of the treatment.
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