[Asperger syndrome: evolution of the concept and current clinical data].

Rev Neurol (Paris)

Service de médecine psychologique pour enfants et adolescents Peyre Plantade, CHU de Montpellier, 291, avenue du Doyen-Gaston-Giraud, 34295 Montpellier cedex 5, France.

Published: May 2008

Although Asperger syndrome is described by international classifications as a category of pervasive developmental disorder (PDD), its validity as a specific entity distinct from autistic disorders remains controversial. The syndrome, first described by Hans Asperger, could not be distinguished from high functioning autism (onset, symptoms, outcome...). However, international classifications propose a distinction between the two syndromes based on a delayed onset, the absence of speech delay, the presence of motor disorders and a better outcome in Asperger syndrome. This categorical differentiation is not confirmed by current studies and in the absence of biological markers, no clinical, neuropsychological or epidemiological criteria makes it possible to distinguish high functioning autism from Asperger syndrome. From a clinical perspective, it is nevertheless of interest to isolate Asperger syndrome from other autistic disorders to propose specific assessment and therapy.

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http://dx.doi.org/10.1016/j.neurol.2008.01.009DOI Listing

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