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Significant differences in drug susceptibility among species in the Candida parapsilosis group. | LitMetric

Significant differences in drug susceptibility among species in the Candida parapsilosis group.

Diagn Microbiol Infect Dis

Division of Infectious Diseases, Department of Medicine, Santa Clara Valley Medical Center, San Jose, CA 95128, USA.

Published: September 2008

AI Article Synopsis

Article Abstract

Candida parapsilosis family has 3 proposed species: C. parapsilosis sensu stricto, Candida orthopsilosis, and Candida metapsilosis. C. parapsilosis sensu stricto had significantly higher caspofungin (CAS) and anidulafungin MICs than C. orthopsilosis or C. metapsilosis; C. metapsilosis was least susceptible to fluconazole. C. parapsilosis sensu stricto more frequently displayed (37%) paradoxical growth in CAS (P < or = 0.02). These species susceptibility differences could affect therapeutic choices.

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http://dx.doi.org/10.1016/j.diagmicrobio.2008.04.019DOI Listing

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