Introduction: Chronic sinusitis with nasal polyps is very often associated with allergy. The results of surgical treatment (Functional Endoscopic Sinus Surgery--FESS) in this group of patients are different and rather poor, especially in long term observations.
The Aim: of our study was to evaluate the results of surgical treatment (FESS) in patients suffering from chronic sinusitis with nasal polyps associated with allergy.
Material And Methods: We study the group of 33 patients with allergy-related polypoid lesions in the nasal cavity and paranasal sinuses. The patients with allergy-related disorder were previously under the control of allergologists and pulmonologists. All the patients underwent functional endoscopic sinus surgery. The patients were evaluated in postoperative period 4-6 years after the surgical treatment. The effectiveness of FESS was assessed on the basis of the nasal cavity endoscopic state and amelioration of symptoms.
Results: The most frequent symptoms were postnasal drip and breathing disturbance through the nose. In 37.5% of patients the recurrence of symptoms was observed in the 4-6 years follow-up period. When we assessed aspirin intolerance syndrome patients this ratio increased to 64.7%.
Conclusion: In the allergy-related patients high rate of recurrence after the FESS treatment is stated in the long term observations.
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http://dx.doi.org/10.1016/S0030-6657(07)70532-2 | DOI Listing |
Radiol Case Rep
March 2025
Department of Radiology and Imaging, Grande International Hospital, Kathmandu, Nepal.
Kartagener syndrome is a rare ciliopathic genetic disorder characterized by a triad of chronic sinusitis, situs inversus, and bronchiectasis. The underlying pathophysiology involves reduced ciliary motility due to defects in ciliary structure and function within the respiratory tract and fallopian tubes. Diagnosis is typically confirmed through imaging studies such as X-rays, CT scans, and echocardiograms, which reveal the abnormal orientation of the heart and other organs.
View Article and Find Full Text PDFTrop Doct
January 2025
Junior Resident, Department of General Medicine, Silchar Medical College and Hospital, Assam, India.
Chronic mesh infections after inguinal hernia repair present significant clinical challenges due to biofilm-mediated resistance, involvement of multidrug-resistant and atypical pathogens, and gaps in preventive strategies. Our case series of four patients highlights critical research gaps, including the overlooked role of atypical pathogens such as , diagnostic challenges in detecting slow-growing or resistant organisms and perioperative sterilisation lapses, especially inconsistent Glutaraldehyde use during late-day operations. Many patients suffered with persistent sinuses and recurrent hernias months after surgery.
View Article and Find Full Text PDFTurk Arch Otorhinolaryngol
January 2025
Yüksekova State Hospital, Department of Otorhinolaryngology and Head & Neck Surgery, Hakkari, Türkiye.
Objective: Inflammatory processes play a role in the etiopathogenesis of chronic rhinosinusitis. Many gene polymorphisms have been associated with inflammation. In this study, we aimed to examine the relationship between angiotensin-converting enzyme insertion/deletion gene polymorphism and chronic rhinosinusitis.
View Article and Find Full Text PDFInflamm Res
January 2025
Department of Otolaryngology, Peking University Third Hospital, Haidian District, No. 49 Huayuan North Road, Beijing, 100191, People's Republic of China.
Background: Dysbiosis of the nasal microbiome is considered to be related to the acute exacerbation of chronic rhinosinusitis (AECRS). The microbiota in the nasal cavity of AECRS patients and its association with disease severity has rarely been studied. This study aimed to characterize nasal dysbiosis in a prospective cohort of patients with AECRS.
View Article and Find Full Text PDFJ Breath Res
January 2025
Faculty of Medicine and Health Technology, Tampere University, Arvo Ylpön Katu 34, Tampere, 33520, FINLAND.
The concentrations of nasal nitric oxide (nNO) vary in patients with chronic rhinosinusitis (CRS) supposedly depending upon whether the paranasal ostia are open or obstructed. Our aim was to assess whether nNO levels and their response to topical xylometazoline (a local vasoconstrictor used to alleviate nasal congestion) in patients with CRS differ between those with open or obstructed ostia and if the results were altered by the use of nasal corticosteroids. Methodology: Sixty-six patients with CRS (43% with nasal polyps) or recurrent acute rhinosinusitis and 23 healthy controls were included.
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