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Prognostic role of osteopontin expression in malignant pleural mesothelioma. | LitMetric
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Prognostic role of osteopontin expression in malignant pleural mesothelioma.

Susanna Cappia Luisella Righi Dario Mirabelli Paolo Ceppi Elisa Bacillo Francesco Ardissone Luca Molinaro Giorgio V Scagliotti Mauro Papotti

Am J Clin Pathol

Department of Clinical and Biological Sciences, University of Torino at St Luigi Hospital, Torino, Italy.

Published: July 2008

Malignant pleural mesothelioma (MPM) represents highly aggressive neoplasms with a mean survival of approximately 10 months. Osteopontin, a glycoprotein involved in cell-matrix interactions correlated with invasion and metastatic spread in several tumors, has recently been proposed as a serum marker of MPM in asbestos-exposed subjects. The aim of this study was to define the prognostic role of osteopontin in MPM. For the study, 32 long-term survivors (>24 months) and a random sample of 69 short-term survivors (

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http://dx.doi.org/10.1309/TWCQV536WWRNEU51DOI Listing

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