Both the finger systolic blood pressure (FSP) and the rewarming test of finger skin are measures of circulation in the finger; the first reflects the vasoconstriction phase and the second the vasodilatation phase. The combinations of the specificity and the sensitivity of these methods were evaluated by a receiver operating characteristic curve (ROC). The material included 37 vibration-induced white finger (VWF) cases, five primary Raynaud's cases, and 37 controls. The specificity of the FSP test was high with regard to the anamnesis of white finger and the test was useful for the diagnosis of Raynaud's phenomenon, but the sensitivity was too low for screening. The rewarming test was useful for screening primary Raynaud's case and possibly for screening disorders in peripheral vasodilative function. The connections between the rewarming test and VWF are not clear and according to the present study the rewarming test was not suitable for screening VWF.
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http://dx.doi.org/10.1136/oem.48.7.480 | DOI Listing |
World J Stem Cells
December 2024
Department of Orthopedics, Children's Hospital of Fudan University & National Children's Medical Center, Shanghai 201102, China.
Background: The gold standard of care for patients with severe peripheral nerve injury is autologous nerve grafting; however, autologous nerve grafts are usually limited for patients because of the limited number of autologous nerve sources and the loss of neurosensory sensation in the donor area, whereas allogeneic or xenografts are even more limited by immune rejection. Tissue-engineered peripheral nerve scaffolds, with the morphology and structure of natural nerves and complex biological signals, hold the most promise as ideal peripheral nerve "replacements".
Aim: To prepare allogenic peripheral nerve scaffolds using a low-toxicity decellularization method, and use human umbilical cord mesenchymal stem cells (hUC-MSCs) as seed cells to cultivate scaffold-cell complexes for the repair of injured peripheral nerves.
Cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia caused by cold-reactive IgM antibodies leading to complement-mediated hemolysis. While CAD-associated venous thromboembolism is recognized, its role in arterial thromboembolic events, particularly ischemic stroke, is poorly defined. We report an 84-year-old woman who developed acute onset upper left extremity weakness following exposure to sub-zero temperatures.
View Article and Find Full Text PDFFertil Steril
December 2024
Reproductive Medicine Center, Boai Hospital of Zhongshan Affiliated to Southern Medical University, Zhongshan, People's Republic of China; The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, People's Republic of China. Electronic address:
Objective: To evaluate whether preimplantation genetic testing for aneuploidy (PGT-A) benefits women of advanced reproductive age (≥38 years old) with a diminished ovarian reserve (not more than three retrieved oocytes).
Design: A retrospective analysis comparing two groups: (a) PGT-A group: women who chose PGT-A and subsequent single re-warmed embryo transfers and (b) non-PGT-A group: women who chose not to genetically test their embryos and underwent subsequent fresh or re-warmed embryo transfers of one to two embryos on days 3 or 5.
Subjects: Two hundred thirty patients underwent PGT-A therapy, with 49 of these individuals undergoing more than one PGT-A cycle.
Med Intensiva (Engl Ed)
November 2024
Department of General Practice, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, No. 3002 Sungang Road, Futian District, Shenzhen, 518035, Guangdong Province, China. Electronic address:
Objective: This study explored the association between body temperature and 28-day septic ICU hospital mortality.
Design: Retrospective cohort analysis.
Setting: 208 ICUs in the United States.
Int J Crit Illn Inj Sci
September 2024
Department of Anaesthesiology and Critical Care Medicine, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
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