AI Article Synopsis
- The study looked at how menopause and treatment length affect bone health in women with hyperthyroidism.
- They measured bone density in 192 women, separating them into groups based on whether they were premenopausal or postmenopausal, and whether they had a short or long treatment course.
- Results showed that women who had longer treatment courses had lower bone density, especially in certain areas of the spine and hip, particularly after menopause.
Article Abstract
Objective: To investigate the effect of the course and menopause on the change of bone mineral density (BMD) in female patients with hyperthyroidism.
Methods: BMDs of hip and lumbar vertebrae were measured by dual-energy X-rays absorptiometry(DEXA) in the female patients (n=192, aged 14 approximately 72). Patients were divided into 2 groups (premenopausal and postmenopausal)and 2 subgroups(short-course and long-course). The BMDs were compared between those of age-matched, weight-matched, height-matched and body mass index matched control subgroups.
Results: In the premenopausal hyperthyroidic patients, only the BMDs of the second and total lumbar vertebrae with long-course were significantly lower than those of short-course group(P< 0.05). In the post-menopausal group with the long-course,each BMD measured had a lower level compared with that with short-course, of which the hip and the second lumber vertebrae were evident (P< 0.01).
Conclusion: The course and menopause have an effect on the BMDs in female patients with hyperthyroidism.
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