Trigeminal trophic syndrome is a rare entity characterized by the presence of ala nasi ulceration, trigeminal anesthesia, and paresthesia. It arises secondary to trigeminal nerve injury. Patients with this diagnosis often undergo repeated skin biopsies to rule out suspected nonmelanoma skin cancer due to the clinical appearance. Recognition of this entity is paramount to avoid unnecessary surgical intervention and to attempt therapy.
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J Family Med Prim Care
November 2024
Department of Oral Medicine and Radiology, CSI College of Dental Sciences and Research, Madurai, Tamil Nadu, India.
Herpes zoster is an acute viral infection caused by the reactivation of the varicella zoster virus. It occurs commonly in immunocompromised adults. Odontalgia may be an early prodromal symptom when herpes zoster involves the oral and maxillofacial region, which lays significant emphasis on the role of a dentist in early diagnosis and treatment of the infection.
View Article and Find Full Text PDFJ Oral Maxillofac Pathol
October 2024
Kasturba Medical College, Manipal, Karnataka, India.
Amidst worldwide reports of adverse oral lesions subsequent to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination, the current systematic review planned to determine the prevalence of adverse oral events in adult individuals (≥18 years) after SARS-CoV-2 vaccination, emphasizing upon the type and dose of vaccine, time of onset, and underlying pathophysiology. The registered protocol (PROSPERO CRD42023421307), conforming with PRISMA guidelines, included an all-inclusive literature search through online databases, consisting of Scopus, PubMed/MEDLINE, Web of Science, Lilacs, Livivo, and PROSPERO, completed on 2 May 2023, followed by assessment of risk of bias by Joana Briggs Institute Evaluation Checklist. Due to the paucity of literature, case reports and case series were included.
View Article and Find Full Text PDFMedicine (Baltimore)
December 2024
Laboratory of Neurobiology, Department of Medical Biology and Genetics, Faculty of Medicine Osijek, J. J. Strossmayer University of Osijek, Osijek, Croatia.
Rationale: Herpes simplex virus 1 establishes a latent infection in trigeminal ganglia. Reactivation causes cold sores, as well as viral keratitis. The purpose of this study was to report potential benefits of using active vitamin D receptor ligands (VDR-agonists) as adjunctive therapies for the treatment of infectious corneal perforations, and prevention of HSV recurrence.
View Article and Find Full Text PDFSpec Care Dentist
December 2024
Department of Oral Medicine, University of Pennsylvania, School of Dental Medicine, Philadelphia, USA.
Introduction: Destruction of the trigeminal (Gasserian) ganglion or peripheral damage to the trigeminal nerve may lead to trigeminal trophic syndrome (TTS), a rare condition characterized by self-inflicted trauma. To date, under 200 cases of TTS are documented in medical literature, with only sparse studies reporting on oral complications secondary to this condition.
Case Report: The following report presents a well-documented case of oral complications associated with TTS in an 83-year-old Caucasian female presenting with right-sided lesions on her nasal ala, scalp, buccal mucosa, and tongue, secondary to self-inflicted injury following their second microvascular decompression for surgical management of trigeminal neuralgia.
WMJ
November 2024
University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
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