The authors analyze rare lung diseases and describe a clinicomorphological case of bronioloalveolar carcinoma of the lung as one of rare bronchopulmonary diseases. According to the WHO histological classification (1999), the tumor is adenocarcinoma that is represented solely by bronchioloalveolar vegetations as a monolayer of the cells lining the walls of pre-existing alveoles without invasion of the stroma, vessels, and pleura. In 1876 Mallaser first described this rare disease in cloven-hoofed animals (Artiodactyla) in Scandinavian countries. Subsequently cases of this disease were also described in human beings.
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Curr Issues Mol Biol
December 2024
Department of Fundamental Pathology, Endocrinology Research Centre, 117036 Moscow, Russia.
Adrenocortical cancer (ACC) is a rare malignant neoplasm originating from the adrenal cortex, presenting limited therapeutic options. An avenue for improving therapeutic efficacy may involve a deeper understanding of the role of adrenocortical stem/progenitor cells in the pathogenesis of this disease. Although existing data suggest stem/progenitor characteristics in certain cell populations within ACC, the challenge remains to identify adrenocortical stem cell markers directly involved in its carcinogenesis.
View Article and Find Full Text PDFIndian Dermatol Online J
April 2024
Department of Dermatology, R.N.T. Medical College, Udaipur, Rajasthan, India.
Pathologica
December 2023
Pathology Unit, Department of Mental and Physical Health and Preventive Medicine, Università degli Studi della Campania "L. Vanvitelli", Naples, Italy.
A solitary peripheral lung nodule was found in the left lung of a 52-year-old man. It was located in the lower lobe and measured 18.5 cm of major axis on chest computed tomography.
View Article and Find Full Text PDFCureus
April 2023
Pathology and Laboratory Medicine, Patna Medical College, Patna, IND.
Background: In 2018, ovarian carcinoma ranked as the eighth most common cancer diagnosed and the leading cause of cancer death in women. High-grade serous carcinoma is the most common histological type seen among malignant cases. A diverse group of neoplasms is seen in the ovary with variable clinical, morphological, and histological features, so assessing the nature of ovarian neoplasms further assists in the treatment of the disease.
View Article and Find Full Text PDFAdv Med Sci
March 2023
Department of Human and Medical Genetics, Vilnius University, Vilnius, Lithuania.
Purpose: The aim of the study was to assess the expression of caspase-8 and procaspase-3 proteins in gastric cancer (GC) cells and non-cancerous mucosa in relation to clinical and morphological characteristics of the tumor, postoperative survival as well as other apoptosis-related proteins.
Materials And Methods: The study included 91 GC patients. Expression of the proteins was assessed using immunohistochemical method.
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