A concentration of 6.4 +/- 0.2 (at 1 SD) x 10(11) virus particles (vp) per milliliter was determined for the adenovirus reference material (ARM) by averaging analytical ultracentrifugation concentration data obtained with refractometric detection with the completely independent concentration reported by the Adenoviral Reference Material Working Group (ARMWG). Using this concentration, the ARM absorptivity factor (in sodium dodecyl sulfate [SDS] at 260 nm) of 1.2+/-0.1 (at 1 SD) x 10(12) vp/ml per OD(260 nm) per centimeter was obtained.
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