Background: When pharmacotherapy for epilepsy fails, surgical options, although efficacious, are highly invasive. We explored whether ablation of the cerebral cortex can be performed utilizing the cerebral venous system.
Methods: Mapping and radiofrequency ablation was performed via the venous system in two pigs.
Results: Eight targeted sites were successfully accessed and four targeted sites successfully ablated via the central cerebral venous network.
Conclusion: Electrophysiological mapping and radiofrequency ablation of the cerebral cortex can be performed via the cerebral veins.
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| http://dx.doi.org/10.1016/j.eplepsyres.2008.03.023 | DOI Listing |
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