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Breast Implant Silicones and B Cell-Mediated Immune Responses: A Systematic Review of Literature.
JPRAS Open
September 2024
Division of Plastic & Reconstructive Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Introduction: Breast implants are under recent scrutiny owing to concerns about their potential for inducing immunological diseases, namely breast implant-associated anaplastic large cell lymphoma and breast implant illness. However, the impact of silicone on biologic systems remains unclear. Therefore, we performed a systematic literature review to evaluate the information available on silicone breast implants and their effect on one arm of the adaptive immune response-B lymphocytes and antibody formation.
View Article and Find Full Text PDFClinical peritonitis from allergy to silicone ventriculoperitoneal shunt.
Clin J Gastroenterol
June 2017
Division of Gastroenterology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Silicones are inorganic compounds that have been used for the purpose of shunting ventricular fluid since the mid-20th century [1]. Complications of ventriculoperitoneal shunts have rarely been attributed to silicone allergy, with only a handful of cases reported in literature. The classic presentation of allergy to silicone ventriculoperitoneal shunt, i.
View Article and Find Full Text PDFStill's-like Disease Induced by Breast Implants in a Middle-Aged Female Health Professional.
Eur J Case Rep Intern Med
January 2017
Department of Internal Medicine, Nicosia University General Hospital, Nicosia, Cyprus.
Unlabelled: We report a case of silicone-induced Still's-like inflammatory syndrome diagnosed after extensive investigation in the department of internal medicine of a secondary hospital. A 45-year-old female healthcare specialist presented with fever, headache, sore throat, myalgia and fatigue. A history of breast augmentation surgery in 2007 was confirmed.
View Article and Find Full Text PDFAntisilicone antibodies are biologically unlikely.
Clin Rheumatol
August 2008
Dow Corning Corporation, Midland, MI, USA.
The association between silicone implants and both antibodies and autoimmune diseases.
Clin Rheumatol
February 2008
Department of Plastic and Reconstructive Surgery, Gaziantep University School of Medicine, Gaziantep, Turkey.
Silicones are widely used materials in many fields of medicine and largely are believed to be biologically inert. However, some investigators have reported that silicone implants are associated with an increased incidence of autoimmune disorders. In this study, we evaluated the capsular tissue of silicone implants and the sera of implant patients and controls for antisilicone antibodies and nonspecific immunoglobulins (IgG, IgA, IgM, and IgE).
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