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Acute myocardial injury after administration of intravenous epinephrine for allergic reaction.
SAGE Open Med Case Rep
June 2020
Department of Internal Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Myocardial injury or infarction in the setting of anaphylaxis can be due to anaphylaxis itself, known as Kounis syndrome, or as a result of treatment with epinephrine. Myocardial ischemia caused by therapeutic doses of epinephrine in the setting of anaphylaxis is a rare event attributed to coronary artery vasospasm. A 41-year-old female with past medical history of recurrent costochondritis, chronic thrombocytopenia, and nonspecific palindromic rheumatism presented to the emergency department with perioral numbness, flushing and throat tightness after a meal containing fish and almonds.
View Article and Find Full Text PDFAnaphylactoid syndrome of pregnancy (ASP) is a widespread, proinflammatory, anaphylactic-like reaction that can occur when amniotic fluid enters the maternal blood circulation. ASP is characterized by four cardinal findings: respiratory distress, altered mental status, hypotension, and disseminated intravascular coagulation. ASP is commonly associated with maternal and neonatal mortality.
View Article and Find Full Text PDFAnaphylactic-like reaction from trimethoprim-sulfamethoxazole in a patient with AIDS.
Int J STD AIDS
June 2016
Infectious Disease Section, Riverside County Regional Medical Center, Moreno Valley, CA, USA.
We report a patient with AIDS who had an anaphylactic-like reaction from trimethoprim-sulfamethoxazole. Clinical suspicion of anaphylaxis should be considered in patients presenting with fever, hypotension, eosinophilia, rash, flushing or pulmonary infiltrates after initial exposure and re-exposure to the medication. This case highlights the need for healthcare professionals to be reminded of the association between this unusual antibiotic reaction resembling sepsis and HIV disease.
View Article and Find Full Text PDFHypersensitivity reactions to rifampin. Pathogenetic mechanisms, clinical manifestations, management strategies, and review of the anaphylactic-like reactions.
Medicine (Baltimore)
November 1999
Section of Infectious Diseases, Hospital de Galdakao, Vizcaya, Spain.
Many of the adverse events induced by rifampin have been considered allergic in origin. The flu-like syndrome and other hypersensitivity reactions seem to be caused by immune complexes, although their pathogenetic mechanisms are not fully elucidated. Many cases have been reported of the flu-like syndrome, thrombocytopenia, hemolytic anemia, and renal failure caused by rifampin.
View Article and Find Full Text PDFDrug hypersensitivity reactions and human immunodeficiency virus disease.
J Acquir Immune Defic Syndr (1988)
December 1992
Department of Family and Community Medicine, San Francisco General Hospital, CA 94110.
Drug hypersensitivity reactions are often observed by clinicians treating patients infected with the human immunodeficiency virus (HIV). For certain drugs, the incidence of these reactions appears to be higher than previously reported in the general population. The best example is trimethoprim-sulfamethoxazole, associated with rash, fever, hematologic disturbances, transaminase elevation, and, less frequently, more severe reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, and anaphylactic-like reactions.
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