White rat experiments have demonstrated that bone matrix osteoinductive activity (the matrix ability to induce ectopic osteogenesis) is in direct proportion with the transplant mass in cases when this mass is within 0 to 0.16% b. m. A higher transplant mass is not associated with elevated osteoinductive activity. When the transplant masses are equal, their osteoinductive activities are in proportion with their sizes. These regularities should be borne in mind when choosing the transplant mass and shape.

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