[Change in the content of serum immunoglobulins A, G, M in patients with pulmonary tuberculosis and alcoholism during antibacterial and anti-alcoholism therapy].

Serum immunoglobulins A, G, M in 93 patients with pulmonary tuberculosis and suffering from alcoholism at the same time (a core group) were investigated in the course of a combined therapy. A control group consisted of 44 pulmonary tuberculosis patients who were nonalcoholics. Examinations were carried out on their admission to a hospital and 3, 6 and 9-12 months after treatment. The findings proved that the patients of the core group had hyperproduction of main serum immunoglobulins. In the course of a complex antibacterial and antialcoholic therapy the IgA values remained high. A disturbed functional activity of B-lymphocytes is likely to be one of the causes leading to a low efficacy of the tuberculosis treatment among alcoholics.