Six new nor-beta-lapachones have been synthesized from reaction of 3-bromo-nor-beta-lapachone with arylamines. These derivatives have potent anticancer properties against several cell lines. Here, we report complete unambiguous assignments of (1)H and (13)C chemical shifts of the new compounds. The assignments were made using a combination of one- and two-dimensional NMR techniques ((1)H, (13)C, (1)H-(1)H COSY, (1)H-(13)C HSQC, and (1)H-(13)C HMBC).
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http://dx.doi.org/10.1002/mrc.2250 | DOI Listing |
Differences/disorders of sex development (DSDs) are a diverse group of congenital conditions that result in disagreement between an individual's sex chromosomes, gonads, and/or anatomical sex. The 46, XY DSD group is vast and includes various conditions caused by genetic variants, hormonal imbalances, or abnormal sensitivity to testicular hormones, leading to varying degrees of under-virilization. A 19-year-old phenotypically normal female from Kakamega, Kenya, presented with primary amenorrhea.
View Article and Find Full Text PDFPlant Dis
January 2025
Instituto Valenciano de Investigaciones Agrarias, Plant Protection and Biotechnology Center, Ctra Moncada-Naquera km 4.5, Moncada, Spain, 46113;
Peach-associated luteovirus (PaLV) belongs to the genus Luteovirus, family Tombusviridae. To date, PaLV has only been reported in peach (Prunus persica) and its presence detected in the Republic of Georgia (Wu et al., 2017), China (Zhou et al.
View Article and Find Full Text PDFJ Chem Phys
January 2025
Voevodsky Institute of Chemical Kinetics and Combustion of Siberian Branch of Russian Academy of Sciences, Institutskaya 3, 630090 Novosibirsk, Russia.
We developed a technique allowing the direct observation of photoinduced charge-transfer states (CTSs)-the weakly coupled electron-hole pairs preceding the completely separated charges in organic photovoltaic (OPV) blends. Quadrature detection of the electron spin echo (ESE) signal enables the observation of an out-of-phase ESE signal of CTS. The out-of-phase Electron-Electron Double Resonance (ELDOR) allows measuring electron-hole distance distributions within CTS and its temporal evolution in the microsecond range.
View Article and Find Full Text PDFOrg Biomol Chem
December 2024
Kangwon National University, Chun Cheon 24341, Korea.
-(tetra-aryl) picket calix[4]pyrrole 1 featuring -fluorophenyl groups at all four -positions in a -configuration has been synthesized and characterized unambiguously using single-crystal X-ray diffraction analysis. This pre-organized system possesses a deep binding pocket created by the four aryl groups so that anions can be accommodated through anion-π interactions and four-point N-H⋯anion hydrogen bonds. Single-crystal X-ray diffraction analysis of the CsF and TEAF (TEA = tetraethylammonium) complexes of receptor 1 unequivocally confirms the formation of 1 : 1 complexes, revealing the binding modes in the solid state.
View Article and Find Full Text PDFForensic Sci Int
December 2024
Tampere University, Faculty of Social Sciences, Arvo building, Arvo Ylpon katu 34, Tampere, Finland.
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