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Organismal Responses to Hypoxemic Challenges.
Adv Exp Med Biol
January 2016
Departments of Environmental Health Sciences, The Johns Hopkins University Medical Institutions, Baltimore, MD, 21205, USA,
As a counterpoint to the volumes of beautiful work exploring how the carotid bodies (CBs) sense and transduce stimuli into neural traffic, this study explored one organismal reflex response to such stimulation. We challenged the anesthetized, paralyzed, artificially ventilated cat with two forms of acute hypoxemia: 10 % O(2)/balance N(2) (hypoxic hypoxia [HH] and carbon monoxide hypoxia [COH]). HH stimulates both CBs and aortic bodies (ABs), whereas COH stimulates only the ABs.
View Article and Find Full Text PDFLast word on Counterpoint: Hypobaric hypoxia does not induce different physiological responses from normobaric hypoxia.
J Appl Physiol (1985)
May 2012
Institut Cochin, INSERM U1016, CNRS UMR8104, Université Paris Descartes, France.
Last word on Point: Counterpoint: Hypobaric hypoxia induces different responses from normobaric hypoxia.
J Appl Physiol (1985)
May 2012
ISSUL Institute of Sport Sciences-Department of Physiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Counterpoint: Hypobaric hypoxia does not induce different responses from normobaric hypoxia.
J Appl Physiol (1985)
May 2012
Institut Cochin, INSERM U1016, CNRS UMR8104, Université Paris Descartes, France.
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