To determine the basic word order in Japanese, oxyhemoglobin concentration changes in the frontal region of 32 healthy men were measured by near-infrared spectroscopy. Our experiment used four types of sentences: (i) subject-object-verb (SOV), (ii) object-subject-verb (OSV), (iii) subject-naze (why)-object-verb (SwhyOV), and (iv) naze (why)-subject-object-verb (whySOV). The results have shown that although oxyhemoglobin changes in the OSV sentences were significantly larger than those in the SOV sentences in the left frontal lobe, such effects were not observed between SwhyOV sentences and whySOV sentences. These results are consistent with the view that both SwhyOV and whySOV are the basic, which suggests that neurolinguistic evidence has the potential to provide an important basis for determining the basic word order in a free word-order language.
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http://dx.doi.org/10.1097/WNR.0b013e3283000825 | DOI Listing |
Exp Brain Res
January 2025
Department of Neurology and Suzhou Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, No. 1055, Sanxiang Road, Suzhou, 215004, Jiangsu Province, People's Republic of China.
This study investigated the relationship between eye movement parameters and cognitive function in patients with mild to moderate Alzheimer's disease (AD). A total of 80 patients with AD (mild and moderate) and 34 normal controls (NC) participated. Neuropsychological assessments were conducted using the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA), while eye movements were recorded using eye-tracking technology.
View Article and Find Full Text PDFBehav Res Methods
January 2025
Institute of Developmental Psychology, Faculty of Psychology, Beijing Normal University, No.19 Xinjiekouwai Street, Haidian District, Beijing, 100875, China.
Over the past few decades, Swahili-English and Lithuanian-English word pair databases have been extensively utilized in research on learning and memory. However, these normative databases are specifically designed for generating study stimuli in learning and memory research involving native (or fluent) English speakers. Consequently, they are not suitable for investigations that encompass populations whose first language is not English, such as Chinese individuals.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Centre for Healthy Brain Ageing (CHeBA), University of New South Wales, UNSW Sydney, NSW, Australia.
Background: Subjective Cognitive Complaints (SCCs) can often precede mild cognitive impairment and dementia longitudinally. While increasingly considered an early prodromal stage of dementia, SCCs can also be a symptom of depression. Previous research found that SCCs in the absence of cognitive impairment, controlling for symptoms of depression, were moderately heritable and genetically associated with memory.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Southern California, Los Angeles, CA, USA.
Background: Optimal cerebral blood flow is crucial to maintaining cognitive function. Cerebrovascular reactivity (CVR) is a dynamic measure of cerebrovascular function which represents the ability of cerebral blood vessels to regulate blood flow in response to vasoactive stimuli. Prior studies have demonstrated an association between impaired CVR and cognitive function in cerebrovascular and neurodegenerative conditions, including cerebral amyloid angiopathy and Alzheimer disease.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Wake Forest School of Medicine, Wake Forest University, Winston-Salem, NC, USA.
Background: Alzheimer's disease (AD) is a world-wide healthcare crisis among older adults. Sex, aging, and apolipoprotein E (APOE) genotype are among the most impactful risk factors for AD. Sleep is beneficial for memory and changes with age.
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