Obstructive sleep apnea (OSA) is a form of sleep disordered breathing characterized by episodes of apnea (during sleep) lasting at least 10 seconds per episode. The apneic periods are associated with arterial hypoxemia and disruption of normal sleep as a result of awakenings. It is increasingly being recognized that OSA is a public health hazard and there is increasing evidence that it is associated with an increase in morbidity (and possibly mortality). Patients with OSA also utilize the healthcare resources at higher rates than control patients long before their diagnosis is confirmed. Early recognition of this condition may lead to earlier treatments (eg, nasal CPAP) with reduction of the risk of cardiovascular diseases such as hypertension, ischemic heart disease, arrhythmias, platelet activation and pulmonary hypertension.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387304 | PMC |
Publication Analysis
Top Keywords
Similar Publications
Research progress on the clinical subtyping of obstructive sleep apnea hypopnea syndrome.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
October 2024
Department of Respiratory and Critical Care Medicine, Second Xiangya Hospital, Central South University, Changsha 410011.
Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common sleep-disordered breathing condition that exhibits a notable degree of heterogeneity, a feature not fully considered in current diagnostic and therapeutic strategies. This article reviews and analyzes research progress in the subtyping of OSAHS from multiple perspectives, including clinical feature-based subtyping, comorbidity-based subtyping, polysomnography (PSG) parameter-based subtyping, and other classification approaches. Existing studies have identified common subtypes based on clinical features and clarified the characteristics of different subgroups in comorbidity-based classifications; the rich data provided by PSG have helped optimize the classification of OSAHS; and multi-dimensional clustering has provided a more precise basis for individualized treatment.
View Article and Find Full Text PDFBilevel positive airway pressure ventilation to prevent hypoxaemia during gastroscopy under sedation in patients at risk of hypoxaemia: study protocol for a prospective randomised controlled trial.
BMJ Open
March 2025
Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
Introduction: During sedation for gastroscopy, hypoxaemia represents the most common adverse event. The objective of this trial is to assess the efficacy and safety of bilevel positive airway pressure (BPAP) for the prevention of hypoxaemia, in comparison with nasal cannula oxygen therapy, among patients predisposed to hypoxaemia during sedation for gastroscopy.
Methods And Analysis: This randomised controlled trial (RCT) will include 616 patients at risk of hypoxaemia when undergoing gastroscopy, including those with advanced age, frailty, American Society of Anesthesiologists grades III-IV, obesity, obstructive sleep apnoea-hypopnoea syndrome, cardiac disease, respiratory disease and diabetes.
Association of Daily Steps Over Time with Adult Asthma Incidence.
J Allergy Clin Immunol
March 2025
Department of Medicine, Vanderbilt University Medical Center, 1161 21(st) Avenue South, Nashville, TN 37232, USA. Electronic address:
Background: Higher daily step counts is associated with reduced risk of many chronic diseases. Increased physical activity improves asthma outcomes. There are no known prevention strategies for adult incident asthma.
View Article and Find Full Text PDFPalatal Perforation Due to Nasal Myiasis in a Patient With Atrophic Rhinitis: A Case Report.
Ear Nose Throat J
March 2025
Department of Otorhinolaryngology and Head and Neck surgery, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.
Atrophic rhinitis (AR) is a chronic nasal disease characterized by atrophy of the nasal mucosa and turbinates. Occasionally, nasal myiasis complicates AR. This case illustrates an uncommon complication of nasal myiasis, palatal perforation.
View Article and Find Full Text PDFCorrection to: Development and external validation of a Nomogram to predict obstructive sleep apnea in Children.
Eur J Pediatr
March 2025
Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!