Spontaneous intracerebral hemorrhage (ICH) has the highest mortality of all cerebrovascular events. Thirty-day mortality approaches 50%, and only 20% of survivors achieve meaningful functional recovery at 6 months. Many clinicians believe that effective therapies are lacking; however, this is changing because of new data on the pathophysiology and treatment of ICH, particularly research establishing the role of medical therapies to promote hematoma stabilization. This article provides updates to a recent publication discussing basic principles of ICH management, including initial stabilization, the prevention of hematoma growth, treatment of complications, and identification of the underlying etiology. Minimally invasive surgery (MIS) to reduce clot size is also discussed, with the goal of preserving neurologic function through reduction in parenchymal damage from edema formation.
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http://dx.doi.org/10.1016/j.ncl.2008.03.002 | DOI Listing |
Front Aging Neurosci
December 2024
Department of Radiology, Qilu Hospital (Qingdao) of Shandong University, Qingdao, China.
Objectives: To investigate the function of the glymphatic system (GS) and its association with neuropsychological tests in spontaneous intracerebral hemorrhage (sICH) by diffusion tensor imaging analysis along the perivascular space (DTI-ALPS).
Methods: This retrospective study included 58 patients with sICH and 63 age- and sex-matched healthy controls (HCs). Partial correlation analyses were performed to examine the relationships between the DTI-ALPS index and radiological as well as clinical data.
World Neurosurg
December 2024
Department of Medicine, Quaid e Azam Medical College, Bahawalpur, Pakistan.
World Neurosurg
December 2024
Department of Neurosurgery and Neurooncology, Medical University of Łódź, Barlicki University Hospital Kopcińskiego 22, Łódź, Poland. Electronic address:
PeerJ
December 2024
Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Background: Spontaneous intracerebral hemorrhage (sICH) is a severe event with high mortality. Recently, evidence has emerged suggesting that malignant solid tumors may increase the risk of sICH through unique cancer-related factors. However, the specific risk factors and clinical characteristics of sICH in patients with malignant solid tumor remain poorly understood.
View Article and Find Full Text PDFClin Neurol Neurosurg
December 2024
Department of Neurosurgery, YueYang People's Hospital, Yueyang, Hunan, China.
Introduction: Primary intraventricular hemorrhage (PIVH) is a rare type of hemorrhagic stroke typically associated with vascular structural abnormalities. However, little is known about the epidemiology and etiology of PIVH caused by non-vascular structural abnormalities. In this study, we aimed to clarify the etiology, clinical characteristics, and prognosis of non-vascular structural-related intraventricular hemorrhage (NVSRIVH).
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