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[Allergy and anaphylaxis].

Ned Tijdschr Geneeskd

July 2024

Tergooi MC, Hilversum. Afd. Intensive Care.

Allergy is a medical condition of frequent occurrence. In the Netherlands approximately 20% of the population has some kind of respiratory allergy, due to pollen and dust mites. The occurrence of allergy on foods, antibiotics, other medications, contrast fluid and insect poison is estimated to be 2% in the adult population.

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This study delves into the rare occurrence of rhabdomyolysis induced by wasp stings, emphasizing its toxic systemic repercussions. Drawing parallels with documented instances of insect bites worldwide, including those by honey bees and Africanized bees, the research explores the correlation between multiple wasp stings and acute renal failure associated with rhabdomyolysis. The venom's active components, such as amines, kinins, and histamine-releasing peptides, underpin toxic systemic reactions, leading to hemolysis, coagulopathy, and severe cytotoxicity-induced acute renal failure.

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Management of infusion-related reactions in cancer therapy: strategies and challenges.

ESMO Open

March 2024

Medical Oncology Department, Centro Hospitalar Universitário do Porto, Porto, Portugal; Oncology Research Unit, UMIB-Unit for Multidisciplinary Research in Biomedicine, ICBAS-School of Medicine and Biomedical Sciences, Universidade do Porto, Porto, Portugal. Electronic address:

Several anticancer therapies have the potential to cause infusion-related reactions (IRRs) in the form of adverse events that typically occur within minutes to hours after drug infusion. IRRs can range in severity from mild to severe anaphylaxis-like reactions. Careful monitoring at infusion initiation, prompt recognition, and appropriate clinical assessment of the IRR and its severity, followed by immediate management, are required to ensure patient safety and optimal outcomes.

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Heparin-induced Anaphylaxis shock.

Qatar Med J

November 2023

Hamad Medical Corporation; Medical Education Doha, Qatar Email:

Article Synopsis
  • A case is presented of a 53-year-old man with End Stage Renal Disease who experienced severe symptoms, including vomiting and a drastic drop in blood pressure, shortly after receiving heparin during dialysis.
  • Despite initial treatment with epinephrine, he required further intervention, ultimately stabilizing with additional medications, highlighting the need for more awareness and research on heparin-induced anaphylaxis.
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Background: Anemia is extremely common among patients admitted to pediatric intensive care. Alternative treatments to transfusions such as intravenous iron must be considered. There are no published data for a prospective intravenous (IV) iron study focused in the critically ill children.

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