AI Article Synopsis

  • Intraventricular meningiomas are rare tumors in the brain that can cause symptoms like headache and increased intracranial pressure.
  • A case study of a 50-year-old man with a clear cell meningioma revealed he experienced fever and inflammatory syndrome, which improved quickly after surgery.
  • The tumor cells tested positive for interleukin-6, indicating a link between the tumor and the inflammatory response; this case is unique as it’s the first reported instance of this type in an adult male linked to systemic inflammation.

Article Abstract

Intraventricular meningiomas are infrequent intracranial tumors. Clinical symptoms are mainly due to an increased intracranial pressure or a direct pressure on the surrounding brain structures. Inflammatory syndrome was described in some patients with chordoid meningiomas. Here we report a case of right intraventricular clear cell meningioma in a 50-year-old man who presented with fever, headache, and inflammatory syndrome. Clinical and biological normalization was rapidly obtained after tumor removal. Immunohistochemical examination showed tumor cells and lymphocytes positivity for the pyrogenic cytokine interleukin-6, with a same intensity. To our knowledge, this is the first case described in the literature concerning an adult man with an intraventricular clear cell meningioma associated with a systemic inflammatory syndrome.

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Source
http://dx.doi.org/10.1016/j.clineuro.2008.04.008DOI Listing

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