Background: The Duke Treadmill Score (DTS) is an established clinical tool for risk stratification of patients referred for exercise testing, but it does not consider age. We aimed to determine if age could improve the prognostic power of the DTS and if so, to modify the DTS nomogram to include age.
Methods: Of 1,959 patients referred for exercise testing from 1997 to 2006, 1,759 male veterans (age range 23-86 years) remained after exclusion of female and patients with heart failure. Cardiovascular mortality was the main outcome considered.
Results: Cox survival analysis was performed entering age and the DTS; both were significant (P
Conclusions: We propose an age-adjusted DTS nomogram that improves the prognostic estimates of average annual CV mortality over the DTS alone. This nomogram requires external validation and extension to women.
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http://dx.doi.org/10.1016/j.ahj.2008.01.025 | DOI Listing |
Osteoarthr Cartil Open
March 2025
Department of Mechanical Engineering and Materials Science, Duke University, United States.
Objective: We sought to measure the deformation of tibiofemoral cartilage immediately following a 3-mile treadmill run, as well as the recovery of cartilage thickness the following day. To enable these measurements, we developed and validated deep learning models to automate tibiofemoral cartilage and bone segmentation from double-echo steady-state magnetic resonance imaging (MRI) scans.
Design: Eight asymptomatic male participants arrived at 7 a.
FASEB J
October 2024
Department of Animal Sciences, Purdue University, West Lafayette, Indiana, USA.
Open Heart
August 2024
Yazd Cardiovascular Research Center, Non-communicable Diseases Research Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Exp Brain Res
October 2024
Department of Basic and Clinical Sciences, University of Nicosia Medical School, 21 Ilia Papakyriakou, Block C, Rm 202, 1700, Nicosia, Cyprus.
Plantarflexors provide propulsion during walking and receive input from both corticospinal and corticoreticulospinal tracts, which exhibit some frequency-specificity that allows potential differentiation of each tract's descending drive. Given that stroke may differentially affect each tract and impair the function of plantarflexors during walking; here, we examined this frequency-specificity and its relation to walking-specific measures during post-stroke walking. Fourteen individuals with chronic stroke walked on an instrumented treadmill at self-selected and fast walking speed (SSWS and FWS, respectively) while surface electromyography (sEMG) from soleus (SOL), lateral gastrocnemius (LG), and medial gastrocnemius (MG) and ground reaction forces (GRF) were collected.
View Article and Find Full Text PDFFunction (Oxf)
July 2024
Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
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