Resolution of secondary alcohols via Carica papaya lipase-catalyzed enantioselective acylation.

Biotechnol Lett

Department of Chemistry, Faculty of Science and Engineering, Konan University, Higashinada-ku, Kobe 658-8501, Japan.

Published: October 2008

The Carica papaya lipase-catalyzed acylation of benzylcarbinols with vinyl hexanoate proceeded smoothly and enantiospecifically (E > 200), affording the R-esters and leaving the S-alcohols intact. Thus, this plant lipase proved to be a promising biocatalyst for the resolution of alcohols as well as for that of carboxylic acids reported earlier.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10529-008-9747-9DOI Listing

Publication Analysis

Top Keywords

carica papaya
8
papaya lipase-catalyzed
8
resolution secondary
4
secondary alcohols
4
alcohols carica
4
lipase-catalyzed enantioselective
4
enantioselective acylation
4
acylation carica
4
lipase-catalyzed acylation
4
acylation benzylcarbinols
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!