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Redefining Ketamine Pharmacology for Antidepressant Action: Synergistic NMDA and Opioid Receptor Interactions?
Am J Psychiatry
January 2025
Biobehavioral Imaging and Molecular Neuropsychopharmacology Section, NIDA, Baltimore (Levinstein, Budinich, Michaelides); Department of Pathology and Experimental Therapeutics, Institute of Neurosciences, University of Barcelona, L'Hospitalet de Llobregat, Barcelona (Bonaventura); Neuropharmacology and Pain Group, Neuroscience Program, IDIBELL-Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, Barcelona (Bonaventura); Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford (Schatzberg); Experimental Therapeutics and Pathophysiology Branch, NIMH, Bethesda (Zarate); Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore (Michaelides).
Ketamine is a racemic compound and medication comprised of ()-ketamine and ()-ketamine enantiomers and its metabolites. It has been used for decades as a dissociative anesthetic, analgesic, and recreational drug. More recently, ketamine, its enantiomers, and its metabolites have been used or are being investigated for the treatment of refractory depression, as well as for comorbid disorders such as anxiety, obsessive-compulsive, and opioid use disorders.
View Article and Find Full Text PDFMethodological Considerations When Studying Resistance-Trained Populations: Ideas for Using Control Groups.
J Strength Cond Res
December 2024
Department of Health, Exercise Science, and Recreation Management, Kevser Ermin Applied Physiology Laboratory, The University of Mississippi, University, Mississippi; and.
Hammert, WB, Dankel, SJ, Kataoka, R, Yamada, Y, Kassiano, W, Song, JS, and Loenneke, JP. Methodological considerations when studying resistance-trained populations: Ideas for using control groups. J Strength Cond Res 38(12): 2164-2171, 2024-The applicability of training effects from experimental research depends on the ability to quantify the degree of measurement error accurately over time, which can be accounted for by including a time-matched nonexercise control group.
View Article and Find Full Text PDFThe Contribution of Muscular Fatigue and Shoulder Biomechanics to Shoulder Injury Incidence During the Bench Press Exercise: A Narrative Review.
J Strength Cond Res
December 2024
School of Kinesiology, University of Michigan, Ann Arbor, Michigan.
Motlagh, JG and Lipps, DB. The contribution of muscular fatigue and shoulder biomechanics to shoulder injury incidence during the bench press exercise: A narrative review. J Strength Cond Res 38(12): 2147-2163, 2024-Participation in competitive powerlifting has rapidly grown over the past two decades.
View Article and Find Full Text PDFThe Effects of a Low-Volume, High-Intensity Preseason Microcycle on Neuromuscular Performance in Collegiate Female Basketball Players.
J Strength Cond Res
December 2024
Jayhawk Athletic Performance Laboratory-Wu Tsai Human Performance Alliance, University of Kansas, University of Kansas, Lawrence, Kansas.
Philipp, NM, Blackburn, SD, Cabarkapa, D, and Fry, AC. The effects of a low-volume, high-intensity pre-season micro-cycle on neuromuscular performance in collegiate female basketball players. J Strength Cond Res 38(12): 2136-2146, 2024-The use of stretch-shortening cycle (SSC)-based measures of vertical jump performance to monitor responses to training exposures is common practice in sport science.
View Article and Find Full Text PDFA Kinetic Enhanced Tuck Jump Assessment Exposes Residual Biomechanical Deficits in Female Athletes 9 Months Post Anterior Cruciate Ligament Reconstruction.
J Strength Cond Res
December 2024
School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, United Kingdom.
Kember, LS, Riehm, CD, Schille, A, Slaton, JA, Myer, GD, and Lloyd, RS. Residual biomechanical deficits identified with the tuck jump assessment in female athletes 9 months after ACLR surgery. J Strength Cond Res 38(12): 2065-2073, 2024-Addressing biomechanical deficits in female athletes after anterior cruciate ligament reconstruction (ACLR) is crucial for safe return-to-play.
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