This study evaluated the effects of environmental calcium and phosphate on wear resistance, strength, and surface morphology of highly viscous glass-ionomers (HVGICs) (Fuji IX Fast [FN] and KetacMolar [KM]) when exposed to acidic conditions. Fabricated specimens were randomly divided into five groups and kept in acidic solutions (pH 3) with varied levels of calcium and phosphate ranging from 0 to 2.4 mM. After 4 weeks of conditioning, the specimens were subjected to wear testing, shear punch, and surface roughness testing as well as SEM evaluation. Multiple comparisons of wear depth (microm), shear strength (MPa), and surface roughness (Ra) between acidic conditions were performed using ANOVA/post-hoc Scheffe's test (p < 0.05). Results showed that FN and KM exposed to acidic conditions had varied wear resistance, shear strength, surface roughness, and structure depending on environmental phosphate level. Increased level of environmental phosphate led to rougher surface, greater wear resistance, and strength of FN and KM than the controls (acid of pH 3). Under SEM, the surface of both FN and KM specimens were covered by numerous small particles when environmental phosphate was high. Results suggest that environmental phosphate may improve wear resistance and shear strength of HVGICs when challenged by acids.
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http://dx.doi.org/10.1002/jbm.b.31140 | DOI Listing |
Environ Sci Pollut Res Int
January 2025
Department Chemical and Food Engineering, UFSC, Florianópolis, 88040-900, SC, Brazil.
Produced water management is a significant challenge for the oil and gas industry. Due to the large volumes and complex composition of this water, treatment requires special attention, resulting in high costs for companies in the sector. Naphthenic acids, known for their recalcitrance, add a layer of complexity to the treatment process.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Department of Neurology, Mayo Clinic, Rochester, MN, USA.
Background: While disease-modifying treatments that reduce Aβ have been recently approved by the FDA, the identification of novel therapeutic targets and strategies that target underlying mechanisms to delay the AD development are still needed. Abnormal brain energy homeostasis and mitochondria dysfunction are observed early in AD. Therefore, the development of treatments to restore these defects could be beneficial.
View Article and Find Full Text PDFBackground: Many putative factors may contribute to the neurodegeneration seen in Alzheimer's Disease (AD), including the build-up of toxic amyloid-beta plaques and the aberrant reactivity of non-neuronal cell types such as astrocytes and microglia. However, the precise contribution of these factors to normal and disease states of neurons remains poorly defined.
Method: We employed in vitro rat neural co-culture models to determine how changes in cell interactions alter the transcriptional response of neural cell types to agents associated with neurodegeneration.
Alzheimers Dement
December 2024
Edith Cowan University, Perth, Western Australia, Australia.
Background: Recently, there has been substantial interest in investigating the role of short-chain fatty acids (SCFAs) and, medium chain fatty acids (MCFA) in the neuroinflammation associated with Alzheimer's disease (AD). Specifically, butyrate (SCFA) and lauric acid (MCFA) have demonstrated potential in alleviating neuroinflammation and reducing toxicity associated with amyloid proteins. Additionally, they have been found to enhance mitochondrial function and reduce neuronal hyperactivity.
View Article and Find Full Text PDFCurr Opin Clin Nutr Metab Care
December 2024
Nutrition Foundation of Italy, Milan, Italy.
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