The prevalence and severity of depressive symptoms among 155 primary caregivers of children with mental health problems were examined along with variables that mediated or moderated the association of child behavior problems with caregivers' depressive symptoms. Forty percent of participants scored 22 or higher on the Center for Epidemiological Studies Depression Scale, indicating that they might have a serious depression. Perceived personal control, subjective distress, and role disruption mediated the association between internalizing child behavior problems and depressive symptoms. Tangible social support moderated the association between internalizing behavior problems and depressive symptoms. Intangible social support moderated the association between externalizing behavior problems and depressive symptoms.
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http://dx.doi.org/10.1016/j.apnu.2007.06.016 | DOI Listing |
Sci Rep
December 2024
School of Physical Education, Shanghai University of Sport, Shanghai, 200438, China.
Objective: This study aimed to examine the levels of physical activity (PA), sleep, and mental health (MH), specifically depression, anxiety, and stress, among Chinese university students. It also aimed to analyze the influencing factors of MH, providing a theoretical foundation for developing intervention programs to improve college students' mental health.
Methods: A stratified, clustered, and phased sampling method was employed.
Sci Rep
December 2024
Neurobiota Research Center, College of Pharmacy, Kyung Hee University, Seoul, 02447, Korea.
To understand the action mechanism of probiotics against postmenopausal symptoms, we examined the effects of Lactococcus lactis P32 (P) and Bifidobacterium bifidum P45 (P), which suppressed interleukin (IL)-6 and receptor activator of nuclear factor-κB (RANK) ligand (RNAKL) expression in Gardnerella vaginalis (Gv)-stimulated macrophages, on vaginitis, osteoporosis, and depression/cognitive impairment (DC) in mice with vaginally infected Gv, ovariectomy (Ov), or Ov/Gv (oG). Oral administration of P or P decreased Gv-induced DC-like behavior and tumor necrosis factor (TNF)-α, IL-6, RANK, and/or RANKL expression in the vagina, bone, hypothalamus, hippocampus, and colon, while Gv-suppressed bone osteoprotegerin and brain serotonin and brain-derived neurotrophic factor (BDNF) levels increased. They partially shifted vaginal and gut dysbiosis in Gv-infected mice to the gut microbiota composition in normal control mice.
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December 2024
Nehme and Therese Tohme Multiple Sclerosis Center, American University of Beirut Medical Center, Riad El-Solh, PO Box 11-0236, 1107 2020, Beirut, Lebanon.
Fatigue is one of the most prevalent and disabling symptoms among patients with MS, but there is limited research investigating the longitudinal determinants of fatigue progression. This study aims to identify the sociodemographic, behavioral and clinical characteristics, and therapeutic regimens that are correlated with worsening fatigue over time in patients diagnosed with MS. This is a retrospective chart review of 483 patients.
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December 2024
Department of Drug Prohibition and Public Security, Criminal Investigation Police University of China, Shenyang, 110035, China.
Methamphetamine use disorder has emerged as a significant public health concern globally. This study endeavors to elucidate the alterations in expression changes of miRNAs in the plasma of methamphetamine use disorder and elucidate the alterations in miRNA expression in the plasma of individuals with methamphetamine use disorder and investigate the relationship between these differentially expressed miRNAs and the disorder itself, cravings for methamphetamine, and associated mental disorders. Furthermore, the study seeks to clarify the expression of downstream target molecules of specific miRNAs in the plasma of methamphetamine use disorder, assess the diagnostic utility of these miRNAs and their target molecules, explore their potential as biomarkers, and identify potential targets for the diagnosis and treatment of methamphetamine use disorder.
View Article and Find Full Text PDFJ Community Psychol
January 2025
School of Humanities, Shanghai Institute of Technology, Shanghai, China.
This study aims to explore the association between community-based social capital, namely clan identity and sense of community (SOC), and perceived neighbourhood walkability (PNW) in relation to depressive symptoms among rural older adults in urbanisation. A sample of 489 older adults in an urbanising county of Western China participated and moderated mediation analysis was utilised. PNW was negatively associated with depressive symptoms, and SOC mediated the focal association.
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