Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Lumbar disc arthroplasty may be the most innovative and exciting development in the history of spinal surgery. Manufacturers and proponents cite the ability of these devices to relieve pain while preserving motion at the disc space. The preservation of motion is hypothesized to lower the risk of adjacent segment disease and, thereby, improve long-term outcomes. However, the devices are expensive and their use is associated with the potential for significant complications above and beyond those seen with lumbar fusion. At the present time, there is no evidence to suggest that the use of disc arthroplasty results in better short- or long-term functional outcomes than fusion in properly selected patients. Furthermore, there is little if any evidence to support the hypothesis that adjacent segment degeneration is an important clinical entity. Although the absence of proof is not the same as the proof of absence, greater efficacy must be demonstrated to offset the increased costs and complications associated with these devices. Therefore, these devices require further long-term study in a controlled environment before widespread application.
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