Objective: To assess the value of tomographic ultrasound imaging (TUI) in the diagnosis of spina bifida in fectuses.
Methods: Eight fetuses suspected of having spina bifida following 2-D ultrasound underwent TUI examination. The fetal spines were observed on the coronal, transverse and sagittal views to confirm the location and severity of the spinal lesions, and the ultrasound findings were compared with the pathological results.
Results: In 6 of the 8 fetuses with spina bifida, TUI obtained clear images demonstrating the presence of the lesions, and the results of TUI diagnosis were consistent with pathological examination of the fetuses.
Conclusions: TUI can clearly visualize spinal bifida in fetuses, and as a useful complementary technique to 2-D ultrasound, TUI may obviously improve the capacity of conventional ultrasound for diagnosis of fetal spina bifida.
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Childs Nerv Syst
January 2025
Department of Neurological Surgery, Children's Hospital, Goiânia, Brazil.
Background: Myelomeningocele (MMC) is the most common type of congenital spinal malformation, typically requiring surgical intervention. While prenatal repair is increasingly favored, postnatal repair remains the standard in many settings. This study aims to evaluate the antibiotics prescribed to neonates with MMC and their correlation with central nervous system (CNS) infection rates following postnatal surgical repair.
View Article and Find Full Text PDFJ Surg Case Rep
January 2025
Department of Surgery, University of Baghdad, College of Medicine, Baghdad, Iraq.
Spinal dysraphism is the incomplete fusion of the neural arch, which can be seen as an occult or open neural tube defect. Meningoceles are a form of open neural tube defect characterized by cystic dilatation of the meninges containing cerebrospinal fluid without the involvement of neural tissue. Neurosurgical intervention is necessary in the newborn period since survival in advancing ages is often impossible.
View Article and Find Full Text PDFToxics
January 2025
Faculdades Pequeno Príncipe Av Iguaçu, 333, 80230-020 Curitiba, Paraná, Brazil.
Neural tube defects (NTDs) are the second most common congenital anomaly and have been widely associated with exposure to pesticides. This systematic review which analyzes the association between parental exposure to pesticides and NTDs was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. The search strategy was designed considering the population, exposure, controls, outcomes, and study design (PECOS).
View Article and Find Full Text PDFAim: Latissimus dorsi is a multi-purpose muscle that can be used to repair defects in many areas of the body. The current study aims to investigate latissimus dorsi morphometry, innervation, vascularization, and variational situations in fetuses.
Material And Methods: Forty-nine fetuses, aged between 15 and 40 weeks of gestation, were examined for the morphological development of the latissimus dorsi.
J Community Genet
January 2025
Red Nacional de Anomalías Congénitas (RENAC), Instituto Nacional de Epidemiología, ANLIS Malbrán, Buenos Aires, Argentina.
Patiens with major congenital anomalies diagnosed prenatally should be referred to and delivered in institutions with the appropriate level of complexity, as this reduces morbidity and mortality. We aimed to assess the prevalence and prenatal diagnosis proportion of selected congenital abnormalities and the complexity levels of birth institutions in a sample of public maternity hospitals in Argentina. Data sources were (1) National Congenital Anomalies Registry, covering the period from 2013 to 2021; and (2) Categorization of birth institutions according to their complexity (high or low).
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